Functional imaging of the human papilla and peripapillary region based on flicker-induced reflectance changes
Functional imaging of the human papilla and peripapillary region based on flicker-induced reflectance changes
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DOI：
10.1016/j.neulet.2004.02.063
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发表时间：
2004-04-29
影响因子：
2.5
通讯作者：
Riva, CE
中科院分区：
文献类型：
--
作者：
Crittin, M;Riva, CE
提出了一种基于双波长光反射率变化（DeltaR%）的眼底神经组织无创功能成像技术。本文研究了由569和600 nm两个光谱分量组成的30 °漫亮度闪烁场对6名正常志愿者Δ R的影响。在569 nm处，视盘所有象限的组平均DeltaR均具有显著性且相似，视盘组织的平均值为-10.7%，视乳头周围区域的平均值为-3.6%。在600 nm处，DeltaR也是显著的，但较小，即椎间盘组织为-3.5%，乳头周围区域为-1.7%。569和600 nm处的变化最可能代表血容量变化。600 nm的反射率没有显示出明显的特征，表明存在闪烁诱导的氧合变化。(C)2004爱思唯尔爱尔兰有限公司保留所有权利。
A non-invasive functional imaging technique of the nervous tissue of the human eye fundus based on two wavelength light reflectance changes (DeltaR%) is presented. The effect of 30degrees diffuse luminance flicker field made of two spectral components (569 and 600 nm) on DeltaR was studied in six normal volunteers. Group averaged DeltaR was significant and similar in all quadrants of the optic disc at 569 nm with a mean equal to - 10.7% for the tissue of the optic disc and - 3.6% for the peripapillary regions. At 600 nm, the DeltaR were also significant but smaller, i.e. - 3.5% for the disc tissue and - 1.7% for the peripapillary region. The changes at 569 and 600 nm represent most probably blood volume changes. The 600 nm reflectance did not show evident features suggesting the presence of flicker-induced oxygenation changes. (C) 2004 Elsevier Ireland Ltd. All rights reserved.