Treatment of Proximal Superficial Caries Lesions on Primary Molar Teeth with Resin Infiltration and Fluoride Varnish versus Fluoride Varnish Only: Efficacy after 1 Year
Treatment of Proximal Superficial Caries Lesions on Primary Molar Teeth with Resin Infiltration and Fluoride Varnish versus Fluoride Varnish Only: Efficacy after 1 Year
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DOI：
10.1159/000275573
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发表时间：
2010-01-01
期刊：
影响因子：
4.2
通讯作者：
Martignon, S.
中科院分区：
文献类型：
--
作者：
Ekstrand, K. R.;Bakhshandeh, A.;Martignon, S.
这项分口研究旨在评估氟化物清漆 (FV) 覆盖的树脂浸润病变与仅 FV 治疗乳磨牙近端病变的疗效。该研究持续了1年。包括在咬翼X光片上检测到乳磨牙上有2个或更多浅表近端病变的儿童。在获得家长书面同意后，50 名儿童每人的两个病变被随机分配到两种治疗方法之一：树脂浸润，然后应用 FV (2.26% F)（测试病变）与仅 FV（对照病变）。治疗前由 2 名临床医生记录所选病变的 ICDAS 评分（检查者间和检查者内部一致性的加权 kappa >0.79）。首次治疗后 6 个月和 12 个月将 FV 应用于测试和对照病灶。 1 年后，获得了 42 名儿童的 ICDAS 评分和 39 名儿童的 X 光片。一位不熟悉该研究的外部检查员对 X 光片进行了两次评分（加权 kappa 0.88）。儿童的基线平均年龄为 7.17 +/- 8 (SD) 0.68，平均 def-s 为 8.1 8 (SD) 6.9。 1 年后，31% 的测试病灶和 67% 的对照病灶的 ICDAS 评分出现进展（p < 0.01）。从放射学上看，23% 的测试病灶和 62% 的对照病灶已进展 (p < 0.01)。因此，树脂浸润/FV 与单独 FV 相比的临床和放射学治疗效果>35%，并且显着。总之，树脂渗透与氟化物清漆相结合似乎有希望控制乳磨牙近端病变的进展。版权所有 (C) 2010 S. Karger AG，巴塞尔
This split-mouth study aimed to assess the efficacy of resin-infiltrated lesions covered by fluoride varnish (FV) versus FV treatment only of proximal lesions on deciduous molar teeth. The study lasted for 1 year. Children with 2 or more superficial proximal lesions on deciduous molar teeth detected on bitewing radiographs were included. After written parental consent, two lesions in each of 50 children were randomly allocated to one of two treatments: resin infiltration followed by FV (2.26% F) application (test lesion) versus only FV (control lesion). The ICDAS scores of the selected lesions were recorded by 2 clinicians before the treatments (weighted kappa for inter-and intra-examiner agreement >0.79). FV was applied to both test and control lesions 6 and 12 months after the first treatment. After 1 year ICDAS scores were obtained for 42 children and radiographs for 39. One external examiner not familiar with the study scored the radiographs twice (weighted kappa 0.88). Baseline mean age of the children was 7.17 +/- 8 (SD) 0.68 and mean def-s was 8.1 8 (SD) 6.9. After 1 year the ICDAS scores of 31% of the test lesions and 67% of the control lesions had progressed (p < 0.01). Radiographically, 23% of the test lesions and 62% of the control lesions had progressed (p < 0.01). Thus, the clinical and radiographic therapeutic effect of both resin infiltration/FV over FV alone was >35% and significant. To conclude, resin infiltration in conjunction with fluoride varnish seems promising for controlling proximal lesion progression on deciduous molar teeth. Copyright (C) 2010 S. Karger AG, Basel