Use of small samples of urine to monitor gonadotrophins in menopausal women.
Use of small samples of urine to monitor gonadotrophins in menopausal women.
复制标题
使用少量尿液样本监测更年期妇女的促性腺激素。
DOI：
10.1016/0009-8981(79)90078-0
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发表时间：
1979
期刊：
影响因子：
--
通讯作者：
J. Livesey
中科院分区：
文献类型：
--
作者：
M. Metcalf;J. Livesey
通过测量少量尿液样本中的促性腺激素与肌酐的比率来跟踪绝经时促性腺激素分泌的增加。对于卵泡刺激素，该比率值与血浆浓度（相关系数：早上第一、上午和下午的尿液样本分别为0.93、0.94和0.93：所有结果均以对数表示）和24小时尿量（0.98、0.96和0.94）密切相关。黄体生成素 (LH) 的可比较数字为 0.94、0.94 和 0.90；以及0.95、0.95和0.90。将促性腺激素与肌酐比率 (I.U./ mmol) 乘以 10 得出接近 24 小时促性腺激素输出 (I.U.) 的数字。
The increased gonadotrophin secretion which occurs at the menopause was followed by measuring gonadotrophin to creatinine ratios in small samples of urine. For follicle stimulating hormone, values of the ratio corresponded closely with both plasma concentration (correlation coefficients: 0.93, 0.94 and 0.93 for first morning, mid-morning and mid-afternoon urine samples: all results expressed as logarithms) and 24-h urine output (0.98, 0.96 and 0.94). Comparable figures for luteinising hormone (LH) were 0.94, 0.94 and 0.90; and 0.95, 0.95 and 0.90. Multiplication of the gonadotrophin to creatinine ratios (I.U./ mmol) by 10 gave a figure close to 24-h gonadotrophin output (I.U.).