Prevalence and associations of dry eye syndrome in an older population: the Blue Mountains Eye Study
Prevalence and associations of dry eye syndrome in an older population: the Blue Mountains Eye Study
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DOI：
10.1046/j.1442-9071.2003.00634.x
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发表时间：
2003-06-01
影响因子：
4
通讯作者：
Wang, JJ
中科院分区：
文献类型：
--
作者：
Chia, EM;Mitchell, P;Wang, JJ
本报告描述了澳大利亚老年人群中自述干眼症的患病率以及与全身和眼部因素的关联。蓝山眼科研究扩展项目的参与者年龄在50岁及以上（平均年龄60.8岁，n = 1174），他们完成了全面的眼部检查和干眼症问卷调查。57.5%的参与者报告至少有一种干眼症症状，其中16.6%报告有中度至重度症状，女性更为常见（年龄调整后的优势比[OR]为1.5，95%置信区间[CI]为1.1 - 2.2）。15.3%的参与者报告有三种或更多症状，女性也更为常见（年龄调整后的OR为1.7，CI为1.2 - 2.4）。未观察到与年龄相关的趋势或显著的眼部关联。在对年龄和性别进行调整后，与干眼症综合征显著相关的全身因素包括关节炎、哮喘、痛风病史，使用皮质类固醇、抗抑郁药和激素替代疗法。在这个老年人群中，干眼症综合征很常见，并且与女性性别和全身性疾病有关。
This report describes the prevalence of self-reported dry eye syndrome and associations with systemic and ocular factors in an older Australian population. Participants of the Extension Blue Mountains Eye Study, aged 50 or older (mean age 60.8 years, n = 1174) completed a comprehensive eye examination and dry eye questionnaire. At least one dry eye symptom was reported by 57.5% of participants, with 16.6% reporting moderate to severe symptoms, more frequent in women (age-adjusted odds ratio [OR] 1.5, 95% confidence interval [CI] 1.1-2.2). Three or more symptoms were reported by 15.3% of participants, also more frequent in women (age-adjusted OR 1.7, CI 1.2-2.4). No age-related trends or significant ocular associations were observed. After adjusting for age and sex, systemic factors significantly associated with dry eye syndrome included history of arthritis, asthma, gout, use of corticosteroids, antidepressants and hormone replacement therapy. In this older population, dry eye syndrome was common and has associations with female gender and systemic diseases.