Heart rate variability as an index of cue reactivity in alcoholics
Heart rate variability as an index of cue reactivity in alcoholics
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DOI：
10.1016/s0006-3223(97)00399-5
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发表时间：
1998-04-01
影响因子：
10.6
通讯作者：
Janakiramaiah, N
中科院分区：
文献类型：
--
作者：
Rajan, I;Murthy, PJNV;Janakiramaiah, N
背景：暴露于条件刺激（如与酒精摄入相关的环境因素）后会产生自主神经反应。心率变异性是在自主控制下的，这可能是对这种反应的一种测量。方法：将20名酗酒者和23名匹配的社交饮酒者（均为男性）置于相同的环境中，分别暴露于中性提示和酒精提示下，记录他们的心电图，采用盲法计算心率活力（HRV）的时频域参数。结果：酒精提示后的R-R区间变异系数和HRV频谱（病频带0.05 ~ 0.15 Hz和0.01 ~ 0.05 Hz）绝对幂，酗酒者明显高于社交饮酒者。平均心率（MHR）不能反映这种差异。结论：HRV模式比MHR模式对线索反应更敏感。(C) 1998生物精神病学学会。
Background: Autonomic responses follow exposure to conditioned stimuli such as contextual factors associated with alcohol ingestion. Heart rate variability is under autonomic control a,td may be a measure of such response.Methods: Twenty alcoholics and 23 matched social drinkers (all male) were exposed to a neutral cue and then an alcohol are in identical settings, during which the Electrocardiogram of these subjects was recorded, Time and frequency domain parameters of heart rate viability (HRV) were computed by a blind rater.Results: Coefficient of variation of R-R intervals and absolute powers of HRV spectrum (ill frequency bands 0.05-0.15 Hz and 0.01-0.05 Hz) following alcohol cue ,I ere significantly higher ill alcoholics than social drinkers. The mean heart rate (MHR) failed to reflect this difference.Conclusions: HRV paradigm appears more sensitive than MHR to measure cue reactivity. (C) 1998 Society of Biological Psychiatry.