NEURONAL-ACTIVITY DURING SLEEP AND COMPLETE BOUTS OF HIBERNATION
NEURONAL-ACTIVITY DURING SLEEP AND COMPLETE BOUTS OF HIBERNATION
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DOI：
10.1152/ajpregu.1988.255.6.r1008
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发表时间：
1988-12-01
影响因子：
--
通讯作者：
HELLER, HC
中科院分区：
文献类型：
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作者：
KRILOWICZ, BL;GLOTZBACH, SF;HELLER, HC
在适温哺乳动物觉醒状态的变化施加强大的影响，主要的神经调节系统。行为状态的变化发生在体温（Tb）大于25摄氏度在冬眠期间。然而，没有关于深度麻木期间唤醒状态变化的信息。在这项研究中，我们使用了脑电图，肌电图，和后丘脑神经元活动的地松鼠（黄鼠），以评估唤醒状态在深冬眠。在冬眠期间，在Tb = 21摄氏度以下没有观察到与快速眼动睡眠相对应的状态。然而，在所有检测的温度下（Tb = 14-36 ℃），动物确实继续循环通过与电生理学定义的觉醒（AW）和非快速眼动（NREM）睡眠相对应的状态。这些结果扩展了以前的观察，冬眠是不是一个均匀的状态。相反，深度麻木主要由一种类似于NREM睡眠的状态组成，被一种AW形式的短间隔周期性地打断。这些状态的周期性变化应该伴随着许多调节系统的性质的变化，并且必须在任何关于冬眠的神经控制的理论中得到解释。
Changes in arousal state in a euthermic mammal exert powerful influences on major neural regulatory systems. Changes in behavioral state occur at body temperature (Tb) greater than 25 degrees C during hibernation. However, no information exists regarding alterations in arousal states during deep torpor. In this study we used a combination of electroencephalographic, electromyographic, and posterior thalamic neuronal activity in ground squirrels (Spermophilus lateralis) to evaluate arousal states during deep hibernation. No state homologous to rapid-eye-movement sleep was observed below Tb = 21 degrees C during hibernation. However, the animals did continue to cycle through states homologous to electrophysiologically defined wakefulness (AW) and non-rapid-eye-movement (NREM) sleep at all temperatures examined (Tb = 14-36 degrees C). These results extend previous observations that hibernation is not a homogeneous state. Instead, deep torpor consists primarily of a state similar to NREM sleep, interrupted periodically by short intervals of a form of AW. These periodic alterations in state should be accompanied by changes in the properties of many regulatory systems and must be accounted for in any theory of the neural control of hibernation.