Case Report: Role of an Iodinated Rectal Hydrogel Spacer, SpaceOAR Vue™, in the Context of Low-Dose-Rate Prostate Brachytherapy, for Enhanced Post-Operative Contouring to Aid in Accurate Implant Evaluation and Dosimetry.
Case Report: Role of an Iodinated Rectal Hydrogel Spacer, SpaceOAR Vue™, in the Context of Low-Dose-Rate Prostate Brachytherapy, for Enhanced Post-Operative Contouring to Aid in Accurate Implant Evaluation and Dosimetry.
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DOI：
10.3389/fonc.2021.810955
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发表时间：
2021
影响因子：
4.7
通讯作者：
Fredman E
中科院分区：
文献类型：
--
作者：
Gross A;Yuan J;Spratt D;Fredman E
我们报告了13例连续前列腺癌患者的病例系列，采用低剂量率（LDR）近距离放射治疗，使用SpaceOAR Vue™，SpaceOAR™水凝胶直肠间隔剂的最新碘化迭代。低和有利的中危患者接受单一治疗，不利的中危患者接受近距离治疗。永久性近距离放射治疗可导致亚急性和晚期直肠毒性，精确的直肠前壁和前列腺后侧面轮廓对于准确的剂量测定以确认植入物的安全性至关重要。在非对比CT成像上清晰可见，spacearvue™可以极大地帮助植入后的轮廓和分析。在LDR近距离治疗的背景下，以前的文献没有描述过，我们证明了放置视觉良好的直肠间隔器的额外临床益处。
We present a case series of 13 consecutive patients with prostate cancer treated with low-dose-rate (LDR) brachytherapy, utilizing SpaceOAR Vue™, the recent iodinated iteration of the SpaceOAR™ hydrogel rectal spacer. Low- and favorable intermediate-risk patients receiving monotherapy and unfavorable intermediate- and high-risk patients undergoing a brachytherapy boost were included. Permanent brachytherapy can result in subacute and late rectal toxicity, and precise contouring of the anterior rectal wall and posterior aspect of the prostate is essential for accurate dosimetry to confirm a safe implant. Clearly visible on non-contrast CT imaging, SpaceOAR Vue™ can substantially aid in post-implant contouring and analysis. Not previously described in the literature in the context of LDR brachytherapy, we demonstrate the added clinical benefit of placing a well-visualized rectal spacer.
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影响因子：
3.3
作者：
Kamran, Sophia C.;McClatchy, David M.;Efstathiou, Jason A.
通讯作者：
Efstathiou, Jason A.
影响因子：
4.7
作者：
Conroy D;Becht K;Forsthoefel M;Pepin AN;Lei S;Rashid A;Collins BT;Lischalk JW;Suy S;Aghdam N;Hankins RA;Collins SP
通讯作者：
Collins SP
DOI：
10.1016/j.ijrobp.2010.05.056
发表时间：
2011-09-01
影响因子：
7
作者：
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通讯作者：
Sandler, Howard
影响因子：
1.9
作者：
Kahn, Jenna;Dahman, Bassam;Moghanaki, Drew
通讯作者：
Moghanaki, Drew
影响因子：
6.2
作者：
Albert, M;Tempany, CM;D'Amico, AV
通讯作者：
D'Amico, AV