238U and 232Th concentrations measured in different medical drugs by using solid-state nuclear track detectors and resulting radiation doses to the skin of patients
238U and 232Th concentrations measured in different medical drugs by using solid-state nuclear track detectors and resulting radiation doses to the skin of patients
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DOI：
10.1007/s41365-016-0045-2
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发表时间：
2016-04
影响因子：
2.8
通讯作者：
M. Misdaq;A. Matrane
中科院分区：
文献类型：
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作者：
M. Misdaq;A. Matrane
摩洛哥的城市人口可免费获得区保健中心医生开具的药品。探讨238 U、232 Th及其衰变产物在患者皮肤上的暴露途径。用固体核径迹探测器（SSNTDs）对各种药物中的238 U和232 Th进行了测量，测量的药物样品中238 U和232 Th的浓度范围为（4.3 ± 0.3）~（11.1 ± 0.7）mBq l-1和（0.49 ± 0.03）~（1.3 ± 0.1）mBq l-1。本文提出了一种新的剂量学模型，该模型基于比α剂量和α粒子剩余能量的概念，用于评估患者应用不同药物后皮肤的辐射剂量。患者皮肤应用不同药物产生的238 U和232 Th系列的最大皮肤总等效剂量为2.8 mSv/年-1 cm-2。
Urban populations in Morocco receive free medical drugs as prescribed by doctors in district health centres. To explore the exposure pathway of238U and232Th and their decay products on the skin of patients, these radionuclides were measured in various medical drugs by using solid-state nuclear track detectors (SSNTDs).The measured concentrations range of238U and232Th in the medical drug samples of interest vary from (4.3 ± 0.3) to (11.1 ± 0.7) mBq l−1and (0.49 ± 0.03) to (1.3 ± 0.1) mBq l−1, respectively. A new dosimetric model, based on the concept of specific alpha-dose and alpha-particle residual energy, was developed for evaluating radiation doses to skin following the application of different medical drugs by patients. The maximum total equivalent effective dose to skin due to the238U and232Th series from cutaneous application of different medical drugs by patients was found to be 2.8 mSv year−1cm−2.