Dual energy imaging using a clinical on-board imaging system
Dual energy imaging using a clinical on-board imaging system
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DOI：
10.1088/0031-9155/58/12/4331
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发表时间：
2013-06-21
影响因子：
3.5
通讯作者：
Roeske, J. C.
中科院分区：
文献类型：
--
作者：
Hoggarth, M. A.;Luce, J.;Roeske, J. C.
双能量(DE)成像包括在两种不同诊断能量下获得千伏(KV)X射线图像，并对这些图像进行加权减影。然后生成第三张突出显示软组织的图像。放射性核素成像已被放射科医生用来辅助检测肺部恶性肿瘤。然而，它还没有在临床上应用于放射治疗。这项研究的目的是评估使用商业车载成像系统进行DE成像的可行性。为此分析构建了一个简单的和拟人化的体模。使用不同的成像能量和毫安，获得了体模的平面千伏图像。编写了使用经验确定的加权因子执行DE减法的软件。用信号-差值-色调比(SDNR)定量评价肿瘤的检出能力。总体而言，DE减影抑制了两个模体中的高密度对象。提供最大SDNR的最佳成像技术为140kVp，1.0 mAs和60kvp，3.2 mAs。基于这一分析，使用商业车载成像系统进行DE减影成像是可行的，并且可能改善接受图像引导放射治疗的肺癌患者的肿瘤可视化。
Dual energy (DE) imaging consists of obtaining kilovoltage (kV) x-ray images at two different diagnostic energies and performing a weighted subtraction of these images. A third image is then produced that highlights soft tissue. DE imaging has been used by radiologists to aid in the detection of lung malignancies. However, it has not been used clinically in radiotherapy. The goal of this study is to assess the feasibility of performing DE imaging using a commercial on-board imaging system. Both a simple and an anthropomorphic phantom were constructed for this analysis. Planar kV images of the phantoms were obtained using varied imaging energies and mAs. Software was written to perform DE subtraction using empirically determined weighting factors. Tumor detectability was assessed quantitatively using the signal-difference-tonoise ratio (SDNR). Overall DE subtraction suppressed high density objects in both phantoms. The optimal imaging technique, providing the largest SDNR with a dose less than our reference technique was 140 kVp, 1.0 mAs and 60 kVp, 3.2 mAs. Based on this analysis, DE subtraction imaging is feasible using a commercial on-board imaging system and may improve the visualization of tumors in lung cancer patients undergoing image-guided radiotherapy.