Patients, Here Comes More Nanotechnology
Patients, Here Comes More Nanotechnology
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DOI：
10.1021/acsnano.6b05610
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发表时间：
2016-09-01
期刊：
影响因子：
17.1
通讯作者：
Park, Wolfgang J.
中科院分区：
文献类型：
--
作者：
Chan, Warren C. W.;Udugama, Buddhisha;Park, Wolfgang J.
我们描述了目前技术专家和临床医生在报告纳米技术诊断设备性能方面的差异。该观点指定了用于评估这些设备的“指标”，并描述了弥合这两个社区之间差距的策略，以加速从学术平台到临床的转化。我们使用最近发表的两篇ACS纳米文章来强调硅纳米线和表面增强拉曼光谱呼吸诊断测试对癌症和哮喘患者的评估。这些研究代表了利用临床参数评估性能的新兴纳米技术设备的一些早期研究。
We describe the current difference in reporting the performance of nanotechnology diagnostic devices between technologists and clinicians. This perspective specifies the "metrics" used to evaluate these devices and describes strategies to bridge the gap between these two communities in order to accelerate the translation from academic bench to the clinic. We use two recently published ACS Nano articles to highlight the evaluation of silicon nanowire and surface-enhanced Raman spectroscopy-breath diagnostic tests for patients afflicted with cancer and asthma. These studies represent some of the earliest studies of emerging nanotechnology devices utilizing clinical parameters to assess performance.