Pulling out the 1%: Whole-Genome Capture for the Targeted Enrichment of Ancient DNA Sequencing Libraries

Pulling out the 1%: Whole-Genome Capture for the Targeted Enrichment of Ancient DNA Sequencing Libraries
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DOI:
10.1016/j.ajhg.2013.10.002
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发表时间:
2013-11-07
影响因子:
9.8
通讯作者:
Bustamante, Carlos D.
Bustamante, Carlos D.
中科院分区:
生物学1区
文献类型:
--
作者:
Carpenter, Meredith L.;Buenrostro, Jason D.;Bustamante, Carlos D.

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大多数古代样本的内源 DNA 含量非常低,由于成本原因,无法对许多有趣的样本进行鸟枪测序。古代 DNA (aDNA) 文库通常包含
Most ancient specimens contain very low levels of endogenous DNA, precluding the shotgun sequencing of many interesting samples because of cost. Ancient DNA (aDNA) libraries often contain