External beam radiation therapy for prostate cancer
External beam radiation therapy for prostate cancer
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DOI：
10.3322/canjclin.50.6.349
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发表时间：
2000-11-01
影响因子：
254.7
通讯作者：
Hanks, GE
中科院分区：
文献类型：
--
作者：
Horwitz, EM;Hanks, GE
患有非转移性前列腺癌的男性有许多治疗选择。35年来，放射治疗一直是治疗这种疾病的主要方法。随着技术的进步和前列腺特异性抗原水平、Gleason评分等预处理预后因素的更好应用，生化和临床结果稳步改善。本文就放射治疗前列腺癌的现状作一综述。使用三维适形和常规技术治疗的结果进行了比较和对比。本文还讨论了辅助激素和粒子束治疗在本病治疗中的适当应用。最后，讨论了放射治疗前列腺癌的毒性和未来发展方向。
Men with non-metastatic prostate cancer have many treatment options. For over 35 years, radiation therapy has been a mainstay of treatment for this disease. With improvements in technology and better use of pretreatment prognostic factors, such as prostate specific antigen level and Gleason score, biochemical and clinical results have steadily improved.This article reviews the current status of radiation therapy in the treatment of prostate cancer. Results of treatment utilizing three-dimensional conformal and conventional techniques are compared and contrasted. The appropriate use of adjuvant hormones and particle beam therapy in the management of this disease is also discussed. Finally, the toxicity and future directions of radiation therapy in the treatment of prostate cancer are addressed.