MACROPHAGE CONTENT OF SOME HUMAN TUMORS
MACROPHAGE CONTENT OF SOME HUMAN TUMORS
复制标题
DOI：
10.1016/s0304-3835(75)94826-0
复制
发表时间：
1975-01-01
期刊：
影响因子：
9.7
通讯作者：
ALEXANDER, P
中科院分区：
文献类型：
--
作者：
GAUCI, CL;ALEXANDER, P
通过制备细胞悬液并测量结合异源抗巨噬细胞血清并在培养物中迅速扩散的细胞的比例，测定了44例手术切除的乳腺肿瘤和黑素瘤中存在的巨噬细胞的数量。不同肿瘤的巨噬细胞含量范围为0- 30%。已知已经转移的恶性肿瘤以及转移性病变含有少于10%的巨噬细胞，而在手术中没有扩散证据的癌症具有广泛不同数量的巨噬细胞。
The number of macrophages present in 44 surgically removed breast tumors and melanomas was determined by making a cell suspension and measuring the proportion of cells which bound a heterologous antimacrophage serum and spread rapidly in culture. The macrophage content of the different tumors ranged from 0-30%. The malignant tumors which were known to have metastasized, as well as metastatic lesions, contained less than 10% macrophages whereas cancers for which there was no evidence of spread at operation had widely varying numbers of macrophages.