Racial/ethnic disparities in the prevalence of gestational diabetes mellitus by BMI.
Racial/ethnic disparities in the prevalence of gestational diabetes mellitus by BMI.
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DOI：
10.2337/dc11-2267
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发表时间：
2012-07
期刊：
影响因子：
16.2
通讯作者：
Ferrara A
中科院分区：
文献类型：
--
作者：
Hedderson M;Ehrlich S;Sridhar S;Darbinian J;Moore S;Ferrara A
研究妊娠期糖尿病（GDM）和BMI类别之间的关联是否因种族/民族而异。在北方加州Kaiser Permanente的一个队列研究中，1995年至2006年期间分娩的123，040名未确诊妊娠前糖尿病的妇女中，我们根据BMI类别和与超重/肥胖相关的人群归因风险（PAR）检查了GDM患病率的种族/民族差异。在所有人种/种族组中，年龄校正的GDM患病率随着BMI（kg/m2）类别的增加而增加。然而，亚洲和菲律宾女性的GDM患病率分别为9.9%和8.5%，BMI为22.0-24.9 kg/m2，而西班牙裔、非西班牙裔白色和非洲裔美国女性的GDM患病率分别为>8.0%，BMI较高，如28-30、34-36和≥37 kg/m2。估计的PAR表明，如果所有孕妇体重正常（BMI <25.0 kg/m2），则可以预防GDM的百分比从非洲裔美国妇女的65%到亚洲妇女的23%不等。临床医生应该意识到，GDM风险增加的BMI阈值因种族/民族而异，即使在亚洲和菲律宾妇女中BMI相对较低，风险也很高。亚洲女性除了体重管理外，还可以从不同的预防策略中受益。
To examine whether the association between gestational diabetes mellitus (GDM) and BMI category varies by racial/ethnic group. In a cohort of 123,040 women without recognized pregravid diabetes who delivered babies between 1995 and 2006 at Kaiser Permanente of Northern California, we examined racial/ethnic disparities in the prevalence of GDM by BMI category and the population-attributable risk (PAR) associated with overweight/obesity. Among all racial/ethnic groups, the age-adjusted prevalence of GDM increased with increasing BMI (kg/m2) category. However, Asian and Filipina women had a prevalence of GDM of 9.9 and 8.5%, respectively, at a BMI of 22.0–24.9 kg/m2, whereas in Hispanic, non-Hispanic white, and African American women, the prevalence of GDM was >8.0% at a higher BMI, such as 28–30, 34–36, and ≥37 kg/m2, respectively. The estimated PARs suggest that the percentage of GDM that could be prevented if all pregnant women were of normal weight (BMI <25.0 kg/m2) ranging from 65% for African American women to only 23% among Asian women. Clinicians should be aware that the BMI thresholds for increased risk of GDM varies by racial/ethnic group and that the risk is high even at relatively low BMI cutoffs in Asian and Filipina women. Asian women may benefit from different prevention strategies in addition to weight management.