Transplantations of heart and limb rudiments between Amblystoma and Triton embryos
Transplantations of heart and limb rudiments between Amblystoma and Triton embryos
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DOI:
10.1002/jez.1400650108
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发表时间:
1933-04-01
影响因子:
--
通讯作者:
Copenhaver, WM
中科院分区:
文献类型:
--
作者:
Copenhaver, WM
Studies were made on the growth rate of forelimbs transplanted between embryos of A. mexi-canum and T. taeniatus alpestris. There was a growth acceleration beyond the donor rate in later larval stages in axolotl-Triton limb grafts similar to the A. tigrinum-punctatum results of Harrison (''24) . In embryonic stages and for several days following yolk resorption, the grafted limbs grew at the donor rate. The apparent acceleration in later stages has been explained by the feeding methods and the evidence indicates that the growth rate of axolotl-Triton limb grafts, as in tigrinum-punctatum limb grafts (Twitty and Schwind, ''28), is intrinsic in the grafted tissue. Axolotl-Triton heart grafts did not exceed the donor growth even though hosts and donors were not maintained at comparable nutrient levels. There was apparently some regulation in accordance with the functional demands of the host species. The hearts possessed an extra chamber due to a regenerated host sinus. Usually the graft pulsated at the host or regenerated sinus rate, although not infrequently heart blocks occurred when the graft pulsated at the donor rate, indicating an intrinsic factor for species rhythm as previously described for tigrinum-punctatum heart grafts.