Tupuseleiamides and basiliskamides, new acyldipeptides and antifungal polyketides produced in culture by a Bacillus laterosporus isolate obtained from a tropical marine habitat
Tupuseleiamides and basiliskamides, new acyldipeptides and antifungal polyketides produced in culture by a Bacillus laterosporus isolate obtained from a tropical marine habitat
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DOI:
10.1021/np0201321
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发表时间:
2002-10-01
影响因子:
5.1
通讯作者:
Andersen, RJ
中科院分区:
文献类型:
--
作者:
Barsby, T;Kelly, MT;Andersen, RJ
Laboratory cultures of PNG 276, a Bacillus laterosporus isolate obtained from coastal waters off Papua New Guinea, have been shown to produce the novel metabolites basiliskamide A (1), basiliskamide B (2), tupuseleiamide A (3), and tupusleiamide B (4). The structures of I to 4 were elucidated by analysis of spectroscopic data and chemical degradation. Basiliskamides A (1) and B (g) show potent in vitro anti-Candida, activity.