Cardiac structure and function, and ventricular-arterial interaction 11 years following a pregnancy with preeclampsia
Cardiac structure and function, and ventricular-arterial interaction 11 years following a pregnancy with preeclampsia
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DOI：
10.1016/j.jash.2016.01.012
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发表时间：
2016-04-01
影响因子：
--
通讯作者：
Kahan, Thomas
中科院分区：
文献类型：
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作者：
Al-Nashi, Maha;Eriksson, Maria J.;Kahan, Thomas
先兆子痫（PE）与急性左心室功能不全相关。这些变化最终是否会解决仍不清楚。本研究评估了15名妊娠11年的PE妇女和16名正常妊娠的对照组妇女的左右心室结构和功能以及心室-动脉相互作用。我们发现正常的左右心室尺寸，收缩功能和整体左心室应变，组间无差异。此外，舒张功能指数、左心房和右心房大小以及氨基末端脑钠肽前体均正常，组间无差异。既往有PE的女性收缩压和舒张压动态血压的夜/日比值受损。然而，两组之间的主动脉僵硬度或心室-动脉耦合指数没有差异。总之，我们无法证明PE 11年后女性的收缩期或舒张期左心室或右心室功能或心室-动脉相互作用的剩余变化。(C)2016年美国高血压学会。All rights reserved.
Preeclampsia (PE) is associated with acute left ventricular dysfunction. Whether these changes eventually resolve remains unclear. This study assessed left and right ventricular structure and function, and ventricular-arterial interaction in 15 women 11 years after a pregnancy with PE and 16 matched control subjects with a normal pregnancy. We found normal left and right ventricular dimensions, systolic function, and global left ventricular strain, with no differences between the groups. In addition, indices of diastolic function, left and right atrial size, and amino-terminal pro-brain natriuretic peptide were normal and did not differ between the groups. Women with a previous PE had impaired night/day ratios for systolic and diastolic ambulatory blood pressure. However, indices of aortic stiffness or ventricular-arterial coupling did not differ between the groups. In conclusion, we could not demonstrate remaining alterations in systolic or diastolic left or right ventricular function, or in ventricular-arterial interaction in women 11 years after PE. (C) 2016 American Society of Hypertension. All rights reserved.