MAGNETIC NANOPARTICLE HYPERTHERMIA IN CANCER TREATMENT.
MAGNETIC NANOPARTICLE HYPERTHERMIA IN CANCER TREATMENT.
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DOI：
10.1142/s1793984410000067
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发表时间：
2010-03
期刊：
影响因子：
0.8
通讯作者：
Hoopes PJ
中科院分区：
文献类型：
--
作者：
Giustini AJ;Petryk AA;Cassim SM;Tate JA;Baker I;Hoopes PJ
目前正在探索通过交变磁场（AMF）激活磁性纳米颗粒（mNPs）作为用于肿瘤的靶向治疗加热的技术。具有不同涂层和靶向剂的各种类型的超顺磁性和铁磁性颗粒允许肿瘤部位和类型特异性。磁性纳米粒子热疗也被研究作为常规化疗和放疗的辅助治疗。这篇综述介绍了一些相关的生物学和材料科学参与的技术发展和当前和未来使用的mNP热疗作为临床癌症治疗。
The activation of magnetic nanoparticles (mNPs) by an alternating magnetic field (AMF) is currently being explored as technique for targeted therapeutic heating of tumors. Various types of superparamagnetic and ferromagnetic particles, with different coatings and targeting agents, allow for tumor site and type specificity. Magnetic nanoparticle hyperthermia is also being studied as an adjuvant to conventional chemotherapy and radiation therapy. This review provides an introduction to some of the relevant biology and materials science involved in the technical development and current and future use of mNP hyperthermia as clinical cancer therapy.