Characterization of immunization secondary analyses using demographic and health surveys (DHS) and multiple indicator cluster surveys (MICS), 2006-2018.

Characterization of immunization secondary analyses using demographic and health surveys (DHS) and multiple indicator cluster surveys (MICS), 2006-2018.
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DOI:
10.1186/s12889-021-10364-0
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发表时间:
2021-02-12
期刊:
影响因子:
4.5
通讯作者:
Danovaro-Holliday MC
Danovaro-Holliday MC
中科院分区:
医学2区
文献类型:
--
作者:
Huang Y;Danovaro-Holliday MC

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全球婴儿免疫覆盖率稳定在85%左右。利用现有的调查数据进行分析,而不仅仅是估计覆盖率,这可能有助于免疫规划更好地调整战略,以覆盖未接种疫苗和接种不足的儿童。在低收入和中等收入国家例行进行的人口与健康调查和多指标类集调查收集免疫接种数据,但疫苗接种覆盖率往往是报告和使用的唯一指标。我们对已发表的免疫相关分析进行了审查,以表征和量化使用DHS和MICS数据库进行的免疫次要分析。我们对2006年至2018年8月期间发表的DHS或MICS的免疫相关次要分析的文献进行了系统检索。我们检索了15个电子数据库,没有语言限制。对于纳入的文献,提取相关信息并进行分析,以总结免疫相关次要分析的特征。结果按照PRISMA指南提供。在识别的1411篇论文中,115篇符合我们的合格标准;此外,一篇文章由泛美卫生组织补充。大多数(77.6%)自2012年以来发表,大多数(68.9%)的第一作者或通讯作者隶属于高收入国家的机构(而不是进行这些调查的LMIC)。调查实施和二次分析出版之间的中位数延迟为5.4年,作者隶属于LMIC机构的论文的中位数出版延迟更长(p < 0.001)。超过80%的已发表分析研究了与特定疫苗或完全免疫相关的因素。质量代理,如报告卡与召回的免疫接种数据的百分比;缺失数据的发生和处理;调查分析是否加权;以及原始调查或分析的潜在偏倚或局限性列表,很少被提及。我们的审查表明,需要做更多的工作,以提高现有人口与健康调查和多指标类集调查数据集的利用率,并提高分析质量,为免疫规划提供信息。这将包括增加在中低收入国家进行的分析的比例,缩短调查执行与发表更多分析之间的时间间隔,并在出版物中列入更多关于调查的定性信息,以便更好地解释结果。在线版本包含补充材料,可通过10.1186/s12889-021-10364-0获得。
Infant immunization coverage worldwide has plateaued at about 85%. Using existing survey data to conduct analyses beyond estimating coverage may help immunization programmes better tailor strategies to reach un- and under-immunized children. The Demographic and Health Survey (DHS) and the Multiple Indicators Cluster Survey (MICS), routinely conducted in low and middle-income countries (LMICs), collect immunization data, yet vaccination coverage is often the only indicator reported and used. We conducted a review of published immunization-related analyses to characterize and quantify immunization secondary analyses done using DHS and MICS databases. We conducted a systematic search of the literature, of immunization-related secondary analyses from DHS or MICS published between 2006 and August 2018. We searched 15 electronic databases without language restrictions. For the articles included, relevant information was extracted and analyzed to summarize the characteristics of immunization-related secondary analyses. Results are presented following the PRISMA guidelines. Among 1411 papers identified, 115 met our eligibility criteria; additionally, one article was supplemented by the Pan American Health Organization. The majority were published since 2012 (77.6%), and most (68.9%) had a first or corresponding author affiliated with institutions in high-income countries (as opposed to LMICs where these surveys are conducted). The median delay between survey implementation and publication of the secondary analysis was 5.4 years, with papers with authors affiliated to institutions in LMIC having a longer median publication delay (p < 0.001). Over 80% of the published analyses looked at factors associated with a specific vaccine or with full immunization. Quality proxies, such as reporting percent of immunization data from cards vs recall; occurrence and handling of missing data; whether survey analyses were weighted; and listing of potential biases or limitations of the original survey or analyses, were infrequently mentioned. Our review suggests that more needs to be done to increase the increase the utilization of existing DHS and MICS datasets and improve the quality of the analyses to inform immunization programmes. This would include increasing the proportion of analyses done in LMICs, reducing the time lag between survey implementation and publication of additional analyses, and including more qualitative information about the survey in the publications to better interpret the results. The online version contains supplementary material available at 10.1186/s12889-021-10364-0.
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