New horizons in radiation oncology. Presidential address, April 13, 1978
New horizons in radiation oncology. Presidential address, April 13, 1978
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放射肿瘤学的新视野。
DOI：
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发表时间：
1979
期刊：
影响因子：
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通讯作者：
J. Fowler
中科院分区：
文献类型：
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作者：
J. Fowler
放射治疗的科学基础比任何其他类型的癌症治疗都更牢固，除了可能手术切除小肿块。如今，实验室的进步比以往任何时候都更快地在临床上发挥作用。高压氧、中子治疗和现在的低氧细胞放射增敏剂的临床试验的时间尺度逐渐缩短，就说明了这一点。每次临床前研究和妊娠时间都比上一次短。然而，在我与这一主题相关的28年中，人们一直在说：“放射疗法将在几年内完成：癌症将通过疫苗预防或通过免疫疗法治愈”。然而，这一时期癌症治疗的主要进展来自放疗，最近来自化疗以及两者与手术的结合。在可预见的未来，只要患者存在可触及的肿块，这种情况似乎可能会继续下去。没有发现病毒...
The scientific foundations of radiotherapy are more strongly based than for any other type of cancer treatment except possibly surgical removal of a small lump. Nowadays advances in the laboratory are put into effect in the clinic more rapidly than ever. This is illustrated by the progressively shorter timescales of the clinical trials in hyperbaric oxygen, then neutron therapy, and now hypoxic-cell radiosensitizers. Each pre-clinical research and gestation time was shorter than the last. And yet throughout the 28 years of my association with the subject people have been saying “radiotherapy will be finished in a few years' time: cancer will be prevented by vaccines or cured by immunotherapy”. However, the major advances in cancer treatment during this period have come from radiotherapy and more recently from chemotherapy and from the combination of both with surgery. This seems likely to continue in the foreseeable future, as long as patients present with a palpable lump. No viruses have been identified ...