Low pathogenic avian influenza (H7N6) virus causing an outbreak in commercial Turkey farms in Chile
Low pathogenic avian influenza (H7N6) virus causing an outbreak in commercial Turkey farms in Chile
复制标题
DOI：
10.1080/22221751.2019.1595162
复制
发表时间：
2019-03-29
影响因子：
13.2
通讯作者：
Hamilton-West, Christopher
中科院分区：
文献类型：
--
作者：
Jimenez-Bluhm, Pedro;Bravo-Vasquez, Nicolas;Hamilton-West, Christopher
2016年底，智利中部的火鸡中发生了H7N6低致病性禽流感病毒疫情。我们的特点是爆发病毒的遗传和抗原特性及其在鸡中的实验传播。我们的研究表明，爆发的病毒是2013年至2017年期间从智利野生鸟类病毒中鉴定出的基因的重配，并显示出对家禽的分子适应性和对金刚烷的抗病毒抗性。此外，这些野生鸟类病毒也能够在实验感染的鸡中传播，这突出表明需要继续监测和改善家禽养殖场的生物安全。
In late 2016, an H7N6 low pathogenic avian influenza virus outbreak occurred in domestic turkeys in Central Chile. We characterized the genetic and antigenic properties of the outbreak virus and its experimental transmission in chickens. Our studies demonstrate that the outbreak virus is a reassortment of genes identified from Chilean wild bird viruses between 2013 and 2017 and displays molecular adaptations to poultry and antiviral resistance to adamantanes. Further, these wild bird viruses are also able to transmit in experimentally infected chickens highlighting the need for continued surveillance and improvement of biosecurity in poultry farms.