Frequent Consumption of Sugar- and Artificially Sweetened Beverages and Natural and Bottled Fruit Juices Is Associated with an Increased Risk of Metabolic Syndrome in a Mediterranean Population at High Cardiovascular Disease Risk
Frequent Consumption of Sugar- and Artificially Sweetened Beverages and Natural and Bottled Fruit Juices Is Associated with an Increased Risk of Metabolic Syndrome in a Mediterranean Population at High Cardiovascular Disease Risk
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DOI：
10.3945/jn.116.230367
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发表时间：
2016-08-01
影响因子：
4.2
通讯作者：
Salas-Salvado, Jordi
中科院分区：
文献类型：
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作者：
Ferreira-Pego, Cintia;Babio, Nancy;Salas-Salvado, Jordi
背景：含糖饮料与代谢综合征（MetS）之间的关系是有争议的。目的：本分析评估了含糖饮料（SSBs）、人工加糖饮料、天然果汁和瓶装果汁的摄入量与心血管疾病（CVD）高风险和基线时无MetS的老年人MetS发病率之间的关系。方法：我们前瞻性地检查了来自PREDIMED （prevention con DIeta MEDiterranea）研究的1868名基线时无MetS的参与者。MetS是根据国际糖尿病联合会、美国心脏协会和国家心脏、肺和血液研究所的最新统一标准定义的。能量和营养摄入量在基线时进行评估，然后每年使用经过验证的137项食物频率问卷进行评估。根据随访期间的平均摄入量估计MetS及其组成部分的多变量调整hr。我们比较了两种最高的消费类别（1-5份和50份/周）和最低的类别（5份/周，消费5份/周）所有类型的饮料都与met及其某些成分的风险增加有关。然而，对于SSBs和瓶装果汁，这些关联必须谨慎解释，因为这一人群的消费频率较低。该试验在clinicaltrials.gov注册为ISRCTN35739639。
Background: The relation between the consumption of sweetened beverages and metabolic syndrome (MetS) is controversial.Objective: This analysis evaluated the associations between intakes of sugar-sweetened beverages (SSBs), artificially sweetened beverages, and natural and bottled fruit juices and the incidence of MetS in elderly individuals at high risk of cardiovascular disease (CVD) and without MetS at baseline.Methods: We prospectively examined 1868 participants free of MetS at baseline from the PREDIMED (PREvencion con DIeta MEDiterranea) study. MetS was defined by using the updated harmonized criteria of the International Diabetes Federation, the American Heart Association, and National Heart, Lung, and Blood Institute. Energy and nutrient intakes were evaluated at baseline and then yearly by using a validated 137-item food-frequency questionnaire. Multivariable-adjusted HRs for MetS and its components were estimated from mean intakes during follow-up. We compared the 2 highest consumption categories (1-5 and >5 servings/wk) with the lowest category (5 servings/wk with consumption of 5 servings/wk of all of the types of beverages analyzed was associated with an increased risk of MetS and some of its components. However, for SSBs and bottled fruit juices these associations must be interpreted with caution because of the low frequency of consumption in this population. This trial was registered at clinicaltrials.gov as ISRCTN35739639.