Factors associated with colonization of Streptococcus mutans in 8-to 32-month-old children: a cohort study
Factors associated with colonization of Streptococcus mutans in 8-to 32-month-old children: a cohort study
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DOI：
10.1111/adj.12113
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发表时间：
2013-12-01
影响因子：
2.1
通讯作者：
Lin, H. C.
中科院分区：
文献类型：
--
作者：
Zhou, Y.;Yang, J. Y.;Lin, H. C.
背景：变形链球菌在幼儿中定植的相关因素尚不清楚。本研究的目的是确定与S。方法：招募了一组225名无龋8个月大的儿童进行研究。每6个月检查一次，直到32个月大，以调查其环境因素、宿主因素和细菌传播因素。在基线和每次检查期间，检查他们牙齿的牙菌斑和牙釉质发育缺陷的存在，以及S。结果：8名儿童（3.6%）显示变形链球菌。8个月龄时的变形菌定植。第14个月、20个月、26个月和32个月时的定植百分比分别为6.0%、16.2%、26.7%和33.5%。结果显示，女性（p = 0.006）、釉质发育不全的儿童（p = 0.024）、出生体重低的儿童（p = 0.005）、食用更多甜食的儿童（p <0.001）和可见菌斑比例较高的儿童（p = 0.020和p = 0.041）更容易被沙门氏菌定植。mutans.Conclusions:变形链球菌在幼儿中的定植与性别、牙釉质发育不全、低出生体重、经常食用甜食和口腔卫生不良有关。
Background: The factors involved in Streptococcus mutans colonization in young children are not clear. The aim of this study was to determine the factors associated with S. mutans colonization in 8- to 32-month-old children.Methods: A group of 225 caries-free 8-month-old children was recruited for the study. They were examined every six months until they were 32 months old to investigate their environmental factors, host factors and bacterial transmission factors. At baseline and during each examination, their teeth were checked for the presence of dental plaque and developmental defects of enamel, and S. mutans plaque status was assessed using a real-time PCR test.Results: Eight children (3.6%) showed S. mutans colonization by the age of 8 months. The percentages of colonization were 6.0% at 14 months, 16.2% at 20 months, 26.7% at 26 months, and 33.5% at 32 months. The results showed that females (p = 0.006), children with enamel hypoplasia (p = 0.024), children with low birth weights (p = 0.005), those who consume more sweets (p < 0.001), and those with a higher proportion of visible plaque (p = 0.020 and p = 0.041) were more likely to be colonized by S. mutans.Conclusions: Streptococcus mutans colonization in young children was associated with gender, tooth enamel hypoplasia, low birth weight, frequent consumption of sweets and poor oral hygiene.