Inventory and characteristics of hormonal contraceptives in France

Inventory and characteristics of hormonal contraceptives in France
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法国激素避孕药的库存和特点

DOI:
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发表时间:
1981
期刊:
影响因子:
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通讯作者:
F. Lewin
F. Lewin
中科院分区:
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文献类型:
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作者:
F. Lewin

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在法国销售的用于避孕的激素类固醇包括通过修饰 17 β 雌二醇和源自 19 去甲睾酮的孕激素而获得的合成雌激素。给药方法为: 1) 联合给药方法,在整个周期内联合雌激素和孕激素; 2)序贯法,仅在周期的第一部分施用雌激素,然后在第二部分施用雌激素孕激素; 3) 迷你药丸或仅服用低剂量孕激素; 4) 在性交后48-72小时内停止孕激素方法或施用非常高剂量的雌激素。雌激素抑制促卵泡激素的分泌,但不抑制黄体生成素的分泌,使子宫内膜萎缩并使宫颈粘液变稠。合并 OC 后,珍珠指数非常接近 0%。本文包含一个图表,按其商业名称列出了在法国出售的所有 OC、其成分、价格和制造商名称。
Hormonal steroids distributed in France for contraceptive use include synthetic estrogens obtained by modification of 17 beta estradiol and progestin derived from 19 nortestosterone. Methods of administration are: 1) the combined method which associates estrogen and progesterone during the whole cycle; 2) the sequential method with estrogen only administered during the first part of the cycle followed by estroprogestational administration during the second part; 3) the mini pill or administration of low dose progestin only; and 4) the discontinued progestational method or administration of estrogen in very high doses during the 48-72 hours following coitus. Estrogens inhibit follicle stimulating hormone secretion but not luteinizing hormone secretion atrophizes the endometrium and thickens cervical mucus. With combined OCs the Pearl index is very near 0%. The article includes a chart listing by their commercial names all OCs available in France their contents price and the name of manufacturer.