Prognostic value of health status in patients with heart failure after acute myocardial infarction
Prognostic value of health status in patients with heart failure after acute myocardial infarction
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DOI：
10.1161/01.cir.0000136991.85540.a9
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发表时间：
2004-08-03
期刊：
影响因子：
37.8
通讯作者：
Spertus, JA
中科院分区：
文献类型：
--
作者：
Soto, GE;Jones, P;Spertus, JA
背景 - 特定疾病的健康状况工具，例如堪萨斯城心肌病问卷 (KCCQ)，可以量化心力衰竭患者的症状、功能限制和生活质量。了解 KCCQ 评分与预后之间的关系可能有助于临床医生解释 KCCQ 评分和对患者进行风险分层。 方法和结果 - 我们在一项由 1516 名近期急性心肌梗死后出现心力衰竭患者组成的前瞻性国际队列中检查了 KCCQ 的预后价值。我们重点关注首次门诊（入组后 4 周）测量的 KCCQ 总分 (KCCQ-os) 与随后 1 年心血管死亡率或住院率 (n = 258，20.3%) 之间的关系。 KCCQ-os 与随后的心血管事件密切相关，评分大于或等于 75 的患者的 1 年无事件生存率为 84%，而评分为 75 的患者的 1 年无事件生存率为 59%
Background - Disease-specific health status instruments such as the Kansas City Cardiomyopathy Questionnaire (KCCQ) can quantify symptoms, functional limitations, and quality of life in patients with heart failure. Understanding the relationship between KCCQ scores and prognosis may assist clinicians in both interpreting KCCQ scores and stratifying risk in patients.Methods and Results - We examined the prognostic value of the KCCQ in a prospective, international cohort of 1516 patients with heart failure after a recent acute myocardial infarction. We focused on the relationship between the KCCQ overall score (KCCQ-os), measured at the first outpatient visit (4 weeks after enrollment), and subsequent 1-year cardiovascular mortality or hospitalization (n = 258, 20.3%). KCCQ-os was strongly associated with subsequent cardiovascular events in that those with a score greater than or equal to75 had an 84% 1-year event-free survival compared with 59% for those with a score