Foveal striate cortex of behaving monkey: single-neuron responses to square-wave gratings during fixation of gaze.
Foveal striate cortex of behaving monkey: single-neuron responses to square-wave gratings during fixation of gaze.
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行为猴的中央凹纹状皮层：注视过程中单神经元对方波光栅的反应。
DOI：
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发表时间：
1977
影响因子：
2.5
通讯作者：
W. H. Talbot
中科院分区：
文献类型：
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作者：
G. Poggio;R. W. Doty;W. H. Talbot
本发明包括某些野牡丹素类似物，其中C-1羧基被伯醇取代，C-13和C-14之间的双键被三键取代。本发明还提供了用于制备上述前列腺素类似物的新的化学方法。这些前列腺素类似物表现出类前列腺素活性，因此可用于与前列腺素相同的药理学目的。这些目的包括降低血压、足月引产、生殖周期调节、胃抗分泌作用等。
This invention comprises certain analogs of the prostaglandins in which the C-1 carboxylic is replaced by a primary alcohol and the double bond between C-13 and C-14 is replaced by a triple bond. Also provided in this invention, are novel chemical processes useful in the preparation of the above prostaglandin analogs. These prostaglandin analogs exhibit prostaglandin-like activity, and are accordingly useful for the same pharmacological purposes as the prostaglandins. Among these purposes are blood pressure lowering, labor induction at term, reproductive-cycle regulation, gastric antisecretory action, and the like.