Digital optical phase conjugation of fluorescence in turbid tissue

Digital optical phase conjugation of fluorescence in turbid tissue
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DOI:
10.1063/1.4745775
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发表时间:
2012-08-20
影响因子:
4
通讯作者:
Yang, Changhuei
Yang, Changhuei
中科院分区:
物理与天体物理2区
文献类型:
--
作者:
Vellekoop, Ivo M.;Cui, Meng;Yang, Changhuei

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我们展示了一种相位共轭荧光的方法。我们的方法,称为参考自由数字光学相位共轭,可以共轭极弱,非相干光信号。它被用来相位共轭荧光从一个珠覆盖有0.5毫米的光散射组织。相位共轭光束重新聚焦到珠子上,并导致光强度局部增加两个数量级以上。潜在的应用是在混浊组织内的成像、光捕获和靶向光化学活化。(C)2012年美国物理学会。[http://dx.doi.org/10.1063/1.4745775]
We demonstrate a method for phase conjugating fluorescence. Our method, called reference free digital optical phase conjugation, can conjugate extremely weak, incoherent optical signals. It was used to phase conjugate fluorescent light originating from a bead covered with 0.5 mm of light-scattering tissue. The phase conjugated beam refocuses onto the bead and causes a local increase of over two orders of magnitude in the light intensity. Potential applications are in imaging, optical trapping, and targeted photochemical activation inside turbid tissue. (C) 2012 American Institute of Physics. [http://dx.doi.org/10.1063/1.4745775]