METHODOLOGICAL ISSUES IN DIARRHEAL DISEASES EPIDEMIOLOGY - DEFINITION OF DIARRHEAL EPISODES
METHODOLOGICAL ISSUES IN DIARRHEAL DISEASES EPIDEMIOLOGY - DEFINITION OF DIARRHEAL EPISODES
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DOI：
10.1093/ije/20.4.1057
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发表时间：
1991-12-01
影响因子：
7.7
通讯作者：
SACK, RB
中科院分区：
文献类型：
--
作者：
BAQUI, AH;BLACK, RE;SACK, RB
回顾胰腺疾病文献，发现胰腺发作的定义存在相当大的差异。使用各种腹泻和腹泻发作定义导致分类错误，影响对社区疾病负担的估计，并降低不同研究结果的可比性。本研究试图通过前瞻性收集的社区监测数据来验证癫痫发作的定义。在比较验证分析中，24小时内出现三次或三次以上稀便或任意次数的稀便含血似乎是腹泻的最佳定义。三天无腹泻似乎是定义新事件的最佳时间。使用不同的定义和使用一个有效的定义的重要性的影响进行了讨论。
A review of the diarrhoeal disease literature reveals considerable variability in the definition of diarrhoeal episodes. The use of various definitions of diarrhoea and episodes leads to misclassification, affects the estimates of the disease burden in communities and reduces comparability of the findings from different studies. This study is an attempt to validate the definition of diarrhoeal episodes using prospectively collected community-based surveillance data. In comparative validation analyses, three or more loose stools or any number of loose stools containing blood in a 24-hour period seemed to be the best definition of diarrhoea. Three intervening diarrhoea-free days seemed to be the optimum to define a new episode. The implications of using differing definitions and the importance of using a validated definition are discussed.