Microcirculation after Achilles tendon rupture correlates with functional and patient-reported outcome Running head : Blood flow may predict tendon healing potential
Microcirculation after Achilles tendon rupture correlates with functional and patient-reported outcome Running head : Blood flow may predict tendon healing potential
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跟腱断裂后的微循环与功能和患者报告的结果相关 跑步头：血流量可以预测肌腱愈合潜力
DOI：
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发表时间：
2017
期刊：
影响因子：
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通讯作者：
P. Ackermann
中科院分区：
文献类型：
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作者：
Praxitelis Praxitelous;G. Edman;P. Ackermann
简介：急性跟腱断裂 (ATR) 患者的愈合过程较长，临床结果各异。微循环血流不良被认为是愈合过程的一个重要因素。然而，微循环是否可以预测愈合结果目前尚不清楚。因此，我们研究了跟腱中的血流是否与 ATR 后患者报告的功能结果相关。方法：使用体内激光多普勒血流测定法评估 9 名急性总 ATR 患者术后两周闭塞后反应性充血期间跟腱双侧微血管血流。术后三个月，使用跟腱总断裂评分（ATRS）评估患者报告的结果。一年后，通过结合经过验证的独立患者报告 (ATRS) 和功能结果（脚跟抬高测试）测量，获得统一的结果评分，即阿基里斯综合结果评分 (ACOS)。结果：一年时患者报告和功能综合结果 ACOS 的改善与受伤肢体较高的最大血流量显着相关（r = 0.777，p = 接受文章本文受版权保护。保留所有权利。0.040）。此外，三个月时患者报告的 ATRS 结局的改善与未受伤肢体的最大血流量与静息血流量之比升高相关（r= 0.809，p= 0.015）。结论：早期肌腱愈合中的血流量与 ATR 后患者的长期报告和功能结果相关。正在愈合的跟腱和对侧跟腱的微循环血流似乎决定了受伤后的愈合潜力。
Introduction: Patients with acute Achilles tendon rupture (ATR) display an extended healing process with varying clinical outcome. Poor microcirculatory blood flow has been suggested to be a significant factor for the healing process. However, whether microcirculation may predict healing outcome has been mostly unknown. Therefore, we investigated if blood flow in the Achilles tendon may be associated with patientreported and functional outcomes after ATR. Methods: In vivo laser Doppler flowmetry was used to assess microvascular blood flow bilateral in the Achilles tendons, during post-occlusive reactive hyperemia, of nine patients with acute total ATR at two weeks post-operatively. At three months post-operatively, patient-reported outcome was assessed using Achilles tendon Total Rupture Score (ATRS). At one year a uniform outcome score, Achilles Combined Outcome Score (ACOS), was obtained by combining validated, independent, patientreported (ATRS) and functional outcome (heel-rise test) measures. Results: An improved combined patient-reported and functional outcome, ACOS, at one year was significantly correlated with higher maximum blood flow (r= 0.777, p= A cc ep te d A rt ic le This article is protected by copyright. All rights reserved. 0.040) in the injured limb. Furthermore, enhanced patient-reported outcome, ATRS, at three months, was associated with an elevated ratio of maximum to resting blood flow (r= 0.809, p= 0.015) in the uninjured limb. Conclusion: Blood flow in early tendon healing is associated with long-term patientreported and functional outcomes after ATR. The microcirculatory blood-flow of both the healing and contralateral Achilles tendon seems to determine the healing potential after injury.