PILATUS:: a two-dimensional X-ray detector for macromolecular crystallography

PILATUS:: a two-dimensional X-ray detector for macromolecular crystallography
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DOI:
10.1016/s0168-9002(02)02044-2
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发表时间:
2003-03-21
影响因子:
1.4
通讯作者:
Tomizaki, T
Tomizaki, T
中科院分区:
物理与天体物理3区
文献类型:
--
作者:
Eikenberry, EF;Brönnimann, C;Tomizaki, T

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瑞士光源公司正在开发一种用于蛋白质晶体学的大型量子限制区X射线探测器。最终的探测器将是2k x 2k像素,覆盖40 x 40 cm(2)。已经测试了一个三模块原型,像素为1120 x 157,有效面积为24.3 x 3.4 cm(2)。在单光子计数模式下,可以检测到峰值计数率超过5 x 10(5)X射线/像素/s的6 keV以上的X射线。给出了组件生产的统计数据和阈值调整的结果。为了证明这种新检测器的潜力,在SLS的光束线6S处收集蛋白质晶体数据。(C)2002 Elsevier Science B. V.保留所有权利。
A large quantum-limited area X-ray detector for protein crystallography is under development at the Swiss Light Source. The final detector will be 2k x 2k pixels covering 40 x 40 cm(2). A three-module prototype with 1120 x 157 pixels covering an active area of 24.3 x 3.4 cm(2) has been tested. X-rays above 6 keV with peak count rates exceeding 5 x 10(5) X-ray/pixel/s could be detected in single photon counting mode. Statistics of module production and results of threshold trimming are presented. To demonstrate the potential of this new detector, protein crystal data were collected at beamline 6S of the SLS. (C) 2002 Elsevier Science B.V. All rights reserved.