Seroprevalence of Histoplasmosis in Somali, Burmese, and Hmong Refugees Residing in Thailand and Kenya
Seroprevalence of Histoplasmosis in Somali, Burmese, and Hmong Refugees Residing in Thailand and Kenya
复制标题
DOI：
10.1007/s10903-017-0595-3
复制
发表时间：
2018-04-01
影响因子：
1.9
通讯作者：
Boulware, David R.
中科院分区：
文献类型：
--
作者：
Bahr, Nathan C.;Lee, Deborah;Boulware, David R.
组织胞浆菌病已知是美国中西部的地方病，但世界上许多地方都有病例报告。近年来，索马里人、苗族人和缅甸人（克伦族）构成了美国最大的难民人口。然而，关于这些人群中荚膜组织浆体感染风险的信息是有限的。本研究使用美国疾病控制与预防中心移民血清库测试了来自索马里、缅甸和苗族赴美难民的100个相似样本。采用酶免疫法检测荚膜组织浆体IgG。总体1%（2/299）的难民血清样品荚膜胞杆菌IgG阳性。99份苗族难民样本中1份呈阳性，100份缅甸难民样本中1份呈阳性。苗族和缅甸难民中荚膜H IgG呈低水平阳性。100名索马里难民未检出IgG阳性。
Histoplasmosis is known to be endemic to the Midwestern United States, but cases have been reported throughout much of the world. Somali, Hmong, and Burmese (ethnically Karen) persons make up some of the largest refugee populations coming the United States in recent years. Yet, information about risk of Histoplasma capsulatum infection amongst these populations is limited. This study used the CDC Migrant Serum Bank to test similar to 100 samples from each of Somali, Burmese, and Hmong U.S.-bound refugees. Samples were tested by enzyme immunoassay for Histoplasma capsulatum IgG. Overall 1% (2/299) of refugee serum samples were positive for H. capsulatum IgG. One of 99 samples obtained from Hmong refugees was positive, and the other positive sample came from among 100 Burmese refugee samples. H capsulatum IgG positivity was detected at low levels in Hmong and Burmese refugees. No IgG positivity was detected among 100 Somali refugees.