Pain and nociception in the clinical context.
Pain and nociception in the clinical context.
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临床背景下的疼痛和伤害感受。
DOI：
10.1098/rstb.1985.0022
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发表时间：
1985
期刊：
影响因子：
--
通讯作者：
P. Nathan
中科院分区：
文献类型：
--
作者：
P. Nathan
将讨论两个主题：（i）有害输入给中枢神经系统带来的变化； (ii) 人类感觉不到疼痛的某些意识状态。将给出一段时间的局部疼痛后中枢神经系统中潜伏的神经活动模式的例子。当这个区域受到刺激时，即使过了一段时间，也会感觉到以前的疼痛。此外，对清醒患者的感觉皮层和丘脑的刺激显示出由持续疼痛引起的永久性变化。据文献研究报道，人类会诱导自己进入催眠状态，以免感到疼痛。在所有这些状态下，交感神经活动都会大大增加，脑电图中的 theta 活动也会增加。
Two subjects will be discussed: (i) the changes brought about in the central nervous system by a noxious input; (ii) certain states of consciousness in which human beings do not feel pain. Examples will be given of a pattern of neural activity being latent in the central nervous system after a period of localized pain. When this region is stimulated, even after a period of years, the previous pain is felt. Also, stimulation of the sensory cortex and thalamus in conscious patients shows permanent changes induced by constant pain. Studies from the literature are reported of human beings inducing trance states in themselves so as not to feel pain. In all of these states there is a great increase in sympathetic activity and an increase in the theta-activity in the electroencephalogram.