DYNAMIC MAGNETIC-RESONANCE-IMAGING FOR THE EVALUATION OF SYNOVITIS IN PATIENTS WITH RHEUMATOID-ARTHRITIS
DYNAMIC MAGNETIC-RESONANCE-IMAGING FOR THE EVALUATION OF SYNOVITIS IN PATIENTS WITH RHEUMATOID-ARTHRITIS
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DOI：
10.1002/art.1780370807
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发表时间：
1994-08-01
影响因子：
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通讯作者：
OHNO, W
中科院分区：
文献类型：
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作者：
TAMAI, K;YAMATO, M;OHNO, W
客观的。探讨磁共振成像（MRI）的表现是否反映类风湿性滑膜炎。方法。对 9 名类风湿性关节炎患者的 10 个受影响的膝盖进行了钆-二亚乙基三胺五乙酸增强的动态成像。信号强度的变化与全膝关节置换术期间获得的滑膜活检标本的病理结果相关。结果。纤维蛋白渗出、细胞浸润、绒毛肥大、血管增殖和肉芽形成程度较高的区域增强程度更大。结论。动态 MRI 可用于评估类风湿滑膜的局部疾病活动度。
Objective. To investigate whether the findings of magnetic resonance imaging (MRI) reflect rheumatoid synovitis.Methods. Dynamic imaging enhanced with gadolinium-diethylenetriamine pentaacetic acid was performed on 10 affected knees of 9 patients with rheumatoid arthritis. Changes in signal intensity were correlated with pathologic findings in synovial biopsy specimens obtained during total knee arthroplasty.Results. Enhancement was greater in regions with a higher degree of fibrin exudation, cellular infiltration, villous hypertrophy, vascular proliferation, and granulation formation.Conclusion. Dynamic MRI can be used for assessing local disease activity in rheumatoid synovium.