Pure squamous cell carcinoma and mixed adenosquamous cell carcinoma of the thyroid gland.
Pure squamous cell carcinoma and mixed adenosquamous cell carcinoma of the thyroid gland.
复制标题
甲状腺的纯鳞状细胞癌和混合腺鳞状细胞癌。
DOI：
10.1002/hed.2890060610
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发表时间：
1984
期刊：
影响因子：
--
通讯作者：
M. Ben
中科院分区：
文献类型：
--
作者：
K. Segal;J. Sidi;A. Abraham;M. Konichezky;M. Ben
本文报告4例单纯鳞状细胞癌和2例鳞状细胞癌与腺癌混合。显然，甲状腺的鳞状细胞癌有可能是由现有的鳞状细胞发展而来的，或者是由滤泡细胞化生的结果。甲状腺鳞状细胞癌的转移和直接扩散更为常见，必须在确诊前予以排除。虽然这些病变的肉眼和显微镜病理没有异常特征，但由化生鳞状细胞排列的滤泡提供了原发性甲状腺肿瘤的强有力的推定证据。这些肿瘤具有相对的耐辐射性和生物学上的高度恶性。治疗的选择是根治性手术切除，这些肿瘤必须在初始阶段更积极地治疗。
Four cases of pure squamous cell carcinoma and two cases of mixed squamous cell and glandular carcinoma are reported. Obviously, there is a possibility that squamous cell carcinoma of the thyroid gland develops from the existing squamous cells or as a result of metaplasia of follicular cells. Metastases and direct extension of squamous cell carcinoma in the thyroid gland are much more frequent and must be excluded before the diagnosis can be established. Although the gross and microscopic pathology of these lesions presents no unusual features, follicles lined by metaplastic squamous cells offer strong presumptive evidence of a primary thyroid neoplasm. These tumors are comparatively radioresistant and biologically highly malignant. The treatment of choice is radical surgical resection, and these neoplasms must be treated more aggressively in the initial stage.