Apparent Young's modulus of vertebral cortico-cancellous bone specimens
Apparent Young's modulus of vertebral cortico-cancellous bone specimens
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DOI：
10.1080/10255842.2011.565751
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发表时间：
2012-01-01
影响因子：
1.6
通讯作者：
Mitton, D.
中科院分区：
文献类型：
--
作者：
El Masri, F.;de Brosses, E. Sapin;Mitton, D.
到目前为止，由于皮质厚度和成像分辨率的原因，不可能从适用于体内的成像模式中得出“椎壳”的特定力学特性。作为第一步，本研究的目标是使用逆方法评估椎体皮质松质骨标本的表观杨氏模量。从22个椎体共采集了22个皮质松质标本。所有试件均在压缩状态下进行试验直至破坏。为了从反方法中计算试样的表观杨氏模量，将生物力学实验的边界条件忠实地再现在有限元模型中，并使用了优化程序。结果表明，表观杨氏模量平均值为374 +/- 208 MPa，范围为87 ~ 791 MPa。通过计算皮质-松质介质的表观杨氏模量，本研究给出了包括结合两种骨组织的外壳在内的整个椎体的有限元力学数据。
Up to now, due to cortical thickness and imaging resolution, it is not possible to derive subject-specific mechanical properties on the 'vertebral shell' from imaging modalities applicable in vivo. As a first step, the goal of this study was to assess the apparent Young's modulus of vertebral cortico-cancellous bone specimens using an inverse method. A total of 22 cortico-cancellous specimens were harvested from 22 vertebral bodies. All specimens were tested in compression until failure. To compute the apparent Young's modulus of the specimen from the inverse method, the boundary conditions of the biomechanical experiments were faithfully reproduced in a finite element model (FEM), and an optimisation routine was used. The results showed a mean of the apparent Young's modulus of 374 +/- 208 MPa, ranging from 87 to 791 MPa. By computing an apparent Young's modulus of a cortico-cancellous medium, this study gives mechanical data for an FEM of an entire vertebra including an external shell combining both bone tissues.