Analysis of pharmacologically isolated components of the ERG
Analysis of pharmacologically isolated components of the ERG
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DOI：
10.1016/s0042-6989(98)00281-8
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发表时间：
1999-05-01
期刊：
影响因子：
1.8
通讯作者：
Bisti, S
中科院分区：
文献类型：
--
作者：
Gargini, C;Demontis, GC;Bisti, S
对正常猫眼和药物分离光感受器(PIII)和双极神经元(PII)成分后的视网膜电信号(ERG)进行了谐波分析。在不同条件下得到的频率响应曲线表明，PII分量的带宽在高于PIII带宽的激励频率范围内扩展。PII对高时间频率刺激的反应增强表明，在光传导级联和双极神经元之间的传输线上存在频率依赖的增益控制。这些过程的一个可能的作用是增强相关的视觉信息，同时选择性地衰减源自传导级联的低频信号。(C)1999爱思唯尔科学有限公司。保留所有权利。
An harmonic analysis was applied to the electroretinogram (ERG) measured in intact cat eyes in control conditions and after pharmacological isolation of the components attributed to photoreceptors (PIII) and bipolar neurons (PII). The frequency response curves obtained in various conditions showed that the bandwidth of the PII component extends over a range of stimulus frequencies higher than the bandwidth of PIII. The enhancement of the PII response to stimuli of high temporal frequency suggests the presence of a frequency dependent gain control located either pre- and/or post-synaptically in the transmission line between the phototransductive cascade and bipolar neurons. A possible role of these processes is to enhance relevant visual information whilst selectively attenuating low frequency signals originating in the transductive cascade. (C) 1999 Elsevier Science Ltd. All rights reserved.