Iterative reconstruction improves detection of in-stent restenosis by high-pitch dual-source coronary CT angiography.
Iterative reconstruction improves detection of in-stent restenosis by high-pitch dual-source coronary CT angiography.
复制标题
迭代重建改善了高螺距双源冠状动脉 CT 血管造影对支架内再狭窄的检测。
DOI：
10.1038/s41598-017-07499-9
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发表时间：
2017-07-31
影响因子：
4.6
通讯作者：
Chen Y
中科院分区：
文献类型：
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作者：
Yang J;Yang X;De Cecco CN;Duguay TM;Chen Z;Tesche C;Schoepf UJ;Chen Y
最近的研究表明，正弦图确认迭代重建（SAFIRE）可以产生更高分辨率的图像，具有更大的鲁棒性，以减少各种成像伪影。对85例患者进行了前瞻性评价，并进行了高螺距螺旋采集CT扫描。测量支架内噪声、信噪比（SNR）、支架-管腔衰减增加比（SAIR）和主观图像质量评分，并比较SAFIRE和滤波反投影（FBP）重建之间的差异。以常规冠状动脉造影为标准。在159枚评价的支架中，SAFIRE在支架内噪声、SNR、SAIR和图像质量评分方面优于FBP，优于FBP上级。在每支架分析中，SAFIRE与FBP重建的敏感性分别为85%与85%，特异性分别为89%与78%，阳性预测值分别为73%与57%，阴性预测值分别为95%与94%，曲线下面积分别为0.87与0.82，尽管这些改善没有达到统计学显著性（P > 0.05）。然而，在小直径支架亚组（≤3 mm; n = 95）中，SAFIRE的特异性（82% vs. 62%）、阳性预测值（66% vs. 50%）和曲线下面积（0.81 vs. 0.70）显著改善（P < 0.05）。因此，SAFIRE图像重建可以改善ISR的评价，特别是在较小的支架中。
Recent studies demonstrated that sinogram affirmed iterative reconstructions (SAFIRE) can produce higher-resolution images with greater robustness for the reduction of various imaging artefacts. Eighty-five patients were prospectively evaluated and underwent a high-pitch spiral acquisition CT scan. In-stent noise, signal-to-noise ratio(SNR), stent-lumen attenuation increase ratio (SAIR), and subjective image quality score were measured and compared between the SAFIRE and Filter back projection (FBP) reconstructions. Conventional coronary angiography served as the standard of reference. In 159 evaluated stents, SAFIRE was superior to FBP with regards to in-stent noise, SNR, SAIR, and image quality score. On per-stent analysis, SAFIRE vs. FBP reconstruction yielded 85% vs. 85%sensitivity, 89% vs. 78%specificity, 73% vs. 57%positive predictive value, 95% vs. 94%negative predictive value, and 0.87 vs. 0.82 area under curve, although these improvements did not reach statistical significance (P > 0.05). However, in the subgroup of small diameter stents (≤3 mm; n = 95), specificity(82% vs. 62%), positive predictive value(66% vs. 50%) and area under curve (0.81 vs. 0.70) improved significantly (P < 0.05) with SAFIRE. SAFIRE image reconstruction can thus improve the evaluation for ISR, especially in smaller stents.