Geant4 simulation of the Elekta XVI kV CBCT unit for accurate description of potential late toxicity effects of image-guided radiotherapy
Geant4 simulation of the Elekta XVI kV CBCT unit for accurate description of potential late toxicity effects of image-guided radiotherapy
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Elekta XVI kV CBCT 装置的 Geant4 模拟可准确描述图像引导放射治疗的潜在晚期毒性效应
DOI：
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发表时间：
2014
影响因子：
3.5
通讯作者：
S. Thomas
中科院分区：
文献类型：
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作者：
F. Brochu;N. Burnet;R. Jena;R. Plaistow;M. Parker;S. Thomas
本文介绍了Elekta XVI锥形束计算机断层扫描（CBCT）机器组件与Geant 4的建模及其对两种常用机器设置的校准数据的验证。初步剂量图模拟CBCT来自这个建模工作。本研究是研究项目GHOST的第一步，旨在通过模拟整个治疗计划中不同来源（成像、治疗射束）的剂量沉积，提高对外部射束放疗患者晚期毒性风险的理解。第二种癌症风险然后将从与辐照剂量和第二种癌症风险相关的不同模型导出。
This paper describes the modelisation of the Elekta XVI Cone Beam Computed Tomography (CBCT) machine components with Geant4 and its validation against calibration data taken for two commonly used machine setups. Preliminary dose maps of simulated CBCTs coming from this modelisation work are presented. This study is the first step of a research project, GHOST, aiming to improve the understanding of late toxicity risk in external beam radiotherapy patients by simulating dose depositions integrated from different sources (imaging, treatment beam) over the entire treatment plan. The second cancer risk will then be derived from different models relating irradiation dose and second cancer risk.
影响因子：
3.8
作者：
ROGERS, DWO;FADDEGON, BA;MACKIE, TR
通讯作者：
MACKIE, TR