SF-6D utility scores for alcohol use disorder status and alcohol consumption risk levels in the US population.
SF-6D utility scores for alcohol use disorder status and alcohol consumption risk levels in the US population.
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DOI：
10.1111/add.15224
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发表时间：
2021-05
期刊：
影响因子：
--
通讯作者：
Wittenberg E
中科院分区：
文献类型：
--
作者：
Barbosa C;Bray JW;Dowd WN;Barnosky A;Wittenberg E
评估由酒精使用障碍(AUD)状态和消费水平定义的亚组的美国人口健康效用。横断面调查。美国的社区环境(即，不包括机构环境)。36,402名美国非机构机构中的成年人(年龄18岁以上)。我们使用全国酒精及相关条件流行病学调查III的12项短表调查(SF-12)数据，计算了世界卫生组织酒精消费风险水平--非常高风险、高风险、中等风险、低风险和额外戒酒水平--的平均短表6维度(SF-6D)效用分数，针对3组：(1)普通人群(n=36 042)，(2)终生AUD个人(n=9925)，以及(3)目前患有AUD的个体(n=5083)，并评估不同消费水平之间的最小重要差异(MID)。每个组都是前一个组的子集。在所有消费风险水平上，普通人群的平均SF-6D效用高于终生或当前AUD患者(两组AUD组分别为0.79和0.76)。对于所有组，SF-6D效用随着消费风险水平降低到非禁欲水平而增加，而将消费从非常高的风险水平降低到任何较低的水平与效用的显著和有意义的改善有关。对于终生或目前患有AUD的人来说，戒除高、中、低风险水平与显著且有意义的更差的效用相关。对于普通人群和有酒精使用障碍病史的个人来说，较高的酒精消费风险水平似乎与较低的健康指数得分有关，这意味着较高的酒精消费与较差的健康相关生活质量有关。
To estimate US population health utilities for subgroups defined by alcohol use disorder (AUD) status and consumption level. Cross-sectional survey. Community settings in the United States (i.e., excluding institutional settings). 36,402 adults (age 18+) in non-institutional settings in the U.S. We used 12-item Short Form Survey (SF-12) data from the National Epidemiologic Survey on Alcohol and Related Conditions III to calculate mean Short Form- 6 dimension (SF-6D) utility scores across World Health Organization alcohol consumption risk levels -- very high risk, high risk, medium risk, low risk, and an additional abstinent level -- for 3 groups: (1) the general population (n = 36 042), (2) individuals with lifetime AUD (n = 9925), and (3) individuals with current AUD (n = 5083), and assessed minimally important differences (MIDs) between consumption levels. Each group is a subset of the previous group. The general population’s mean SF-6D utility was higher than that of individuals with lifetime or current AUD across all consumption risk levels (0.79 vs. 0.76 for both AUD groups). For all groups, SF-6D utilities increased as consumption risk level decreased to non-abstinent levels, and reducing consumption from very high risk to any lower level was associated with a statistically significant and meaningful improvement in utility. For individuals with lifetime or current AUD, becoming abstinent from high, medium, and low risk levels was associated with significantly and meaningfully worse utilities. Higher alcohol consumption risk levels appear to be associated with lower health index scores, for the general population and individuals with a history of alcohol use disorder, meaning that higher alcohol consumption is associated with worse health-related quality of life.
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