Lactation is associated with an increase in slow-wave sleep in women
Lactation is associated with an increase in slow-wave sleep in women
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DOI：
10.1046/j.1365-2869.2002.00315.x
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发表时间：
2002-12-01
影响因子：
4.4
通讯作者：
Edwards, N
中科院分区：
文献类型：
--
作者：
Blyton, DM;Sullivan, CE;Edwards, N
主要的生理变化发生在分娩和哺乳期开始后，包括雌激素和孕酮的撤回，从而增加循环催乳素（PRL）。众所周知，在其他情况下，其他循环激素的变化会改变睡眠结构。因此，我们的目的是评估是否睡眠结构的改变，在完全哺乳期妇女作为一个结果与哺乳期激素的变化。对12名完全母乳喂养的妇女（B/F）、12名年龄匹配的对照妇女（CTRL）和7名选择奶瓶喂养婴儿的产后妇女（BOTTLE）进行了描述性比较研究。母亲年龄，婴儿年龄和体重指数（BMI）在所有三组之间相似。我们使用便携式计算机P系列进行了夜间多导睡眠图。三组女性的总睡眠时间（TST）和快速眼动（REM）睡眠时间相似。然而，B F组女性的慢波睡眠（SWS）显著增加，与对照组（86 +/- 22 min，与B/F组相比P < 0.001）和BOTTLE组（63 +/- 29 min，与B/F组相比P <0.001）相比，SWS为182 +/- 41 min。与CTRL和BOTTLE相比，B/F中轻度非快速眼动（NREM）睡眠代偿性减少。对于在完全母乳喂养婴儿的妇女中发生的睡眠结构改变，最可能的解释是循环PRL的增加，这发生在哺乳期妇女中。增强SWS可能是支持产后母乳喂养的另一个重要因素。
Major physiological changes occur following parturition and the onset of lactation, including the withdrawal of oestrogen and progesterone, with a consequent increase in circulating prolactin (PRL). Changes in other circulating hormones are well known to alter sleep architecture in other circumstances. We therefore aimed to assess whether sleep architecture is altered in fully lactating women as a result of hormonal changes associated with lactation. A descriptive comparison study was undertaken on 12 fully breastfeeding women (B/F), 12 age-matched control women ( CTRL), and seven postnatal women who had chosen to bottle-feed their infants (BOTTLE). Maternal age, infant age and body mass index (BMI) were similar between all three groups. We performed overnight polysomnography utilizing the Portable Compumedics P-series. The total sleep time (TST) and rapid eye movement ( REM) sleep time were similar in the three groups of women. However, B F women demonstrated a marked increase in slow wave sleep (SWS), 182 +/- 41 min compared with CTRL ( 86 +/- 22 min, P < 0.001 compared with B/F) and BOTTLE subjects (63 +/- 29 min, P < 0.001 compared with B/F). There was a compensatory reduction in light non-rapid eye movement (NREM) sleep in B/F when compared with CTRL and BOTTLE. The most likely explanation for the altered sleep architecture noted to occur in women who are fully breastfeeding their infants is an increase in circulating PRL, which occurs in lactating women. Enhanced SWS may be another important factor to support breastfeeding in the postnatal period.