Survival Following Mitral Valve Replacement for Mitral Regurgitation due to Coronary Artery Disease
Survival Following Mitral Valve Replacement for Mitral Regurgitation due to Coronary Artery Disease
复制标题
冠状动脉疾病二尖瓣关闭不全二尖瓣置换术后的生存率
DOI：
10.1161/01.cir.60.2.39
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发表时间：
1979
期刊：
影响因子：
37.8
通讯作者：
H. Gold
中科院分区：
文献类型：
--
作者：
M. Radford;R. A. Johnson;M. Buckley;W. Daggett;R. Leinbach;H. Gold
摘要 1970 年至 1975 年间，有 46 名因冠状动脉疾病导致二尖瓣反流而接受二尖瓣置换术的患者被确定。四十名患者在同一手术中接受了主动脉冠状动脉搭桥手术。术前左心室射血分数超过0.35的22例患者术后第四年的生存率为73%，术前左心室射血分数为35%以下的16例患者的术后第四年生存率为38%，二尖瓣置换时行动脉瘤切除术的8例患者的术后第四年生存率为25%（前一组与后两组相比，p < 0.05）。 41 名患者术前出现的心力衰竭在大多数长期幸存者中得到了改善。冠状动脉疾病的血管造影范围以及是否在心肌梗塞的急性期（13 名患者在 2 个月内）或慢性期进行二尖瓣置换术均与生存率没有明显相关。
SUMMARY Forty-six patients who underwent mitral valve replacement for mitral regurgitation due to coronary artery disease during 1970-1975 were identified. Forty patients underwent aortocoronary bypass procedures at the same operation. The survival rate at the fourth postoperative year was 73% in the 22 patients in whom the preoperative left ventricular ejection fraction exceeded 0.35, 38% in the 16 patients in whom the preoperative left ventricular ejection fraction was 35% or less, and 25% in the eight patients in whom aneurysmectomy was performed at the time of mitral valve replacement (p < 0.05 for the former group compared to the latter two groups). Heart failure, present preoperatively in 41 patients, was improved in most of the longterm survivors. Neither the angiographic extent of coronary artery disease nor whether mitral valve replacement was performed in the acute (within 2 months in 13 patients) or chronic phase of myocardial infarction were distinctly correlated with survival.