MINT: the Molecular INTeraction database.
MINT: the Molecular INTeraction database.
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DOI：
10.1093/nar/gkl950
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发表时间：
2007-01
影响因子：
14.9
通讯作者：
Cesareni, Gianni
中科院分区：
文献类型：
--
作者：
Chatr-aryamontri, Andrew;Ceol, Arnaud;Palazzi, Luisa Montecchi;Nardelli, Giuliano;Schneider, Maria Victoria;Castagnoli, Luisa;Cesareni, Gianni
分子相互作用数据库（MINT）旨在以结构化格式存储有关分子相互作用（MIS）的信息，通过从同行评审期刊上发表的工作中提取实验细节。目前，薄荷团队将策划工作集中在蛋白质之间的物理相互作用上。遗传或计算推断的相互作用不包括在数据库中。在过去的四年中，薄荷进行了广泛的修订。新版本的MINT基于完全改建的数据库结构，该结构提供了更有效的数据探索和分析，其特征是带有更丰富注释的条目。在过去的几年中，精选的物理交互的数量已超过95000。可以通过基于Web的接口和FTP服务器在交互式和批处理模式中自由地在线访问整个数据集。现在，薄荷包括作为综合添加的同源物，是从模型生物体中与直系同源蛋白实验的人类蛋白质之间相互作用的数据库（）。
The Molecular INTeraction database (MINT, ) aims at storing, in a structured format, information about molecular interactions (MIs) by extracting experimental details from work published in peer-reviewed journals. At present the MINT team focuses the curation work on physical interactions between proteins. Genetic or computationally inferred interactions are not included in the database. Over the past four years MINT has undergone extensive revision. The new version of MINT is based on a completely remodeled database structure, which offers more efficient data exploration and analysis, and is characterized by entries with a richer annotation. Over the past few years the number of curated physical interactions has soared to over 95 000. The whole dataset can be freely accessed online in both interactive and batch modes through web-based interfaces and an FTP server. MINT now includes, as an integrated addition, HomoMINT, a database of interactions between human proteins inferred from experiments with ortholog proteins in model organisms ().