ORGANIZATION OF FIRST AND SECOND SOMESTHETIC REGIONS (S1 AND S2) IN RAT THALAMUS
ORGANIZATION OF FIRST AND SECOND SOMESTHETIC REGIONS (S1 AND S2) IN RAT THALAMUS
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DOI：
10.1002/cne.901240207
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发表时间：
1965-01-01
影响因子：
2.5
通讯作者：
EMMERS, R
中科院分区：
文献类型：
--
作者：
EMMERS, R
通过电生理学、立体毒性和组织学方法的结合研究了大鼠视丘脑的组织。在任何一种准备中多次插入单极记录电极，以系统地探索那些接收感觉输入的丘脑区域。电极的尖端足够小，可以检测单位活动以及缓慢的电位。通过在所有立体定位维度上使用灵敏的微驱动器，记录位点以250和300μ的距离间隔。对于每个记录站点，地图都是由外围投影场组成的，在触觉刺激下，会引起强、中强或弱反应。由冷冻方法切割的切片重建记录电极造成的穿刺，并重建丘脑内记录部位的几何排列。在大鼠丘脑中发现了两个用于感觉投射的丘脑区域（SI 和 SII）。它们与先前描述的大鼠大脑皮层的第一和第二感觉区域相似。丘脑区域包含腹基底核复合体。在相对较大的 SI 区域中，仅存在身体的对侧投影。鼻子在整个投影区域中都有广泛的体现，而后躯则投影在 SI 的极端前外侧位置中发现的少量丘脑组织上。区域SII相对较小。它位于 SI 的后外侧。动物的身体被重新呈现，但这次是双边的；吻部位于背侧，后躯位于腹侧。
Organization of the rat somesthetic thalamus was studied by a combination of electrophysiologic, stereotoxic, and histologic methods. A monopolar recording electrode was inserted numerous times in any one preparation to explore systematically those thalamic regions which receive somesthetic input. The tip of the electrode was small enough to detect unit activity as well as slow potentials. The recording sites were spaced at 250 and 300 [mu] distances by using sensitive microdrives in all stereotaxic dimensions. For each recording site maps were made of the peripheral projection fields which, upon tactile stimulation, evoked strong, medium strong, or weak responses. Punctures made by the recording electrode were reconstructed from sections cut by the freezing method and the geometric arrangement of the recording sites within the thalamus was reconstituted. Two thalamic regions for somesthetic projection (SI and SII) were found in the rat thalamus. They are similar to the first and the second somesthetic areas previously described with the rat cerebral cortex. The thalamic regions encompass the ventrobasal nuclear complex. In the relatively large region of SI there is contralateral projection of the body only. The snout is extensively represented throughout this projection region whereas the hindquarters project on a smaller amount of thalamic tissue found in the extreme anterolateral position of SI. Region SII is relatively small. It is situated posterolaterally to SI. The animal''s body is represented anew but this time bilaterally; snout dorsomedially, hindquarters ventrolaterally.