Supportive care needs and psychological distress and/or quality of life in ambulatory advanced colorectal cancer patients receiving chemotherapy: a cross-sectional study
Supportive care needs and psychological distress and/or quality of life in ambulatory advanced colorectal cancer patients receiving chemotherapy: a cross-sectional study
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DOI：
10.1093/jjco/hyx152
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发表时间：
2017-12-01
影响因子：
2.4
通讯作者：
Akechi, Tatsuo
中科院分区：
文献类型：
--
作者：
Sakamoto, Nobuhiro;Takiguchi, Shuji;Akechi, Tatsuo
接受化疗的晚期结直肠癌患者有各种支持性护理需求，这些需求与心理困扰和生活质量有关。虽然目前许多晚期结直肠癌患者持续接受化疗，但很少有关于这些患者的支持性护理需求的研究结果。本研究的目的是调查患者的感知需求及其与心理困扰和/或生活质量的关系，并阐明需求未满足程度高的患者的特征。接受化疗的门诊结直肠癌患者被要求完成简短的支持性护理需求调查问卷，该问卷涵盖五个需求领域（卫生系统和信息、心理、身体、护理和支持以及性需求）、医院焦虑和抑郁量表以及欧洲癌症研究和治疗组织生活质量问卷。有100例患者的完整数据。几乎所有十大最常见的未满足需求都属于心理领域。患者总需求与心理困扰（r = 0.65, P < 0.001）和生活质量（r = -0.38, P < 0.001）显著相关。多元回归分析显示，女性与更高的总需求显著相关。患者需求与心理困扰和/或生活质量之间存在的中度到强烈的关联表明，响应患者需求的干预措施可能是改善心理困扰和提高生活质量的一种可能策略。应更仔细地评估女性患者的需求。
Advanced colorectal cancer patients receiving chemotherapy had various supportive care needs, and those needs were associated with both psychological distress and quality of life.Although currently many advanced colorectal cancer patients continuously receive chemotherapy, there are very few findings with regard to the supportive care needs of such patients.The purposes of this study were to investigate the patients' perceived needs and the association with psychological distress and/or quality of life, and to clarify the characteristics of patients with a high degree of unmet needs. Ambulatory colorectal cancer patients who were receiving chemotherapy were asked to complete the Short-Form Supportive Care Needs Survey questionnaire, which covers five domains of need (health system and information, psychological, physical, care and support, and sexuality needs), the Hospital Anxiety and Depression Scale and the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire.Complete data were available for 100 patients. Almost all of the top 10 most common unmet needs belonged to the psychological domain. The patients' total needs were significantly associated with both psychological distress (r = 0.65, P < 0.001) and quality of life (r = -0.38, P < 0.001). A multiple regression analysis revealed that the female gender was significantly associated with higher total needs.The moderate to strong associations that exist between patients' needs and psychological distress and/or quality of life suggest that interventions that respond to patients' needs may be one possible strategy for ameliorating psychological distress and enhancing quality of life. Female patients' needs should be evaluated more carefully.