Evaluation of the Block Matching deformable registration algorithm in the field of head-and-neck adaptive radiotherapy

Evaluation of the Block Matching deformable registration algorithm in the field of head-and-neck adaptive radiotherapy
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DOI:
10.1016/j.ejmp.2013.09.001
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发表时间:
2014-05-01
影响因子:
3.4
通讯作者:
Noel, A.
Noel, A.
中科院分区:
医学3区
文献类型:
--
作者:
Huger, S.;Graff, P.;Noel, A.

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背景和目的:比较块匹配可变形配准(DIR)和刚性图像配准(RIR)对头颈部多模式CT到锥束CT(CBCT)配准的准确性。材料和方法:采用10例患者的计划CT和每周CBCT。采用DIR或RIR将髓管(MC)、甲状软骨(TC)、舌骨(HB)和颌下腺(SMG)等体积从CT图像移位到CBCT图像。在每个CBCT上将移位的体积与这些体积的手工描绘进行比较。用于分析的相似性参数为:骰子相似指数(DSI)、95%-Hausdorff距离(95%-HD)和体积差(Cc)。结果:DIR显示MC的体积差的主要平均值为-1.4cc,显示有限的欠分割。DIR限制了DSI和95%-HD的变异性。它显著改善了TC和Hb的DSI和除SMG外的所有结构的95%-HD。DIR显示MC、TC、Hb和SMG的平均95%-HD(Mm)分别为3.01+/-0.80、5.33+/-2.51、4.99+/-1.69、3.07±-1.31。RIR分别为3.92+/-1.86、6.94+/-3.98、6.44+/-3.37和3.41+/-2.25。结论:块匹配是可变形多模式CT到CBCT配准的有效算法。95%-HD的值对于其在累积剂量计算中的应用的持续发展是有用的。(C)2013年意大利菲西卡医学协会。爱思唯尔有限公司出版。保留所有权利。
Background and purpose: To compare the accuracy of the Block Matching deformable registration (DIR) against rigid image registration (RIR) for head-and-neck multi-modal images CT to cone-beam CT (CBCT) registration.Material and methods: Planning-CT and weekly CBCT of 10 patients were used for this study. Several volumes, including medullary canal (MC), thyroid cartilage (TC), hyoid bone (HB) and submandibular gland (SMG) were transposed from CT to CBCT images using either DIR or RIR. Transposed volumes were compared with the manual delineation of these volumes on every CBCT. The parameters of similarity used for analysis were: Dice Similarity Index (DSI), 95%-Hausdorff Distance (95%-HD) and difference of volumes (cc).Results: With DIR, the major mean difference of volumes was - 1.4 cc for MC, revealing limited under-segmentation. DIR limited variability of DSI and 95%-HD. It significantly improved DSI for TC and HB and 95%-HD for all structures but SMG. With DIR, mean 95%-HD (mm) was 3.01 +/- 0.80, 5.33 +/- 2.51, 4.99 +/- 1.69, 3.07 +/- 1.31 for MC, TC, HB and SMG, respectively. With RIR, it was 3.92 +/- 1.86, 6.94 +/- 3.98, 6.44 +/- 3.37 and 3.41 +/- 2.25, respectively.Conclusion: Block Matching is a valid algorithm for deformable multi-modal CT to CBCT registration. Values of 95%-HD are useful for ongoing development of its application to the cumulative dose calculation. (C) 2013 Associazione Italiana di Fisica Medica. Published by Elsevier Ltd. All rights reserved.