Mid-pregnancy vitamin D levels and postpartum depression

Mid-pregnancy vitamin D levels and postpartum depression
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DOI:
10.1016/j.ejogrb.2014.05.017
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发表时间:
2014-08-01
影响因子:
2.6
通讯作者:
Guclu, Serkan
Guclu, Serkan
中科院分区:
医学4区
文献类型:
--
作者:
Gur, Esra Bahar;Gokduman, Ayse;Guclu, Serkan

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目的:产后抑郁(PPD)是一种常见的疾病,产后10%-15%的产后妇女会受到影响,对母亲和新生儿都有负面影响。最近的研究表明,低水平的维生素D与情绪不佳和抑郁有关。这项前瞻性研究的目的是评估妊娠中期PPD与血清25-羟基维生素D3(25(OH)D3)水平的可能关联。25(OH)D3是一种可靠的维生素D测量方法。研究设计:来源人群包括2012年6月至2012年10月在Sifa大学Bornova Health Research and Application Hospital的所有怀孕24周至28周的孕妇。为了更好地评估维生素D水平和PPD之间的可能影响,具有患PPD风险的特征的人被排除在研究之外。研究组于孕中期测定血清25(OH)D3水平。血清25(OH)D3浓度
Objectives: Postpartum depression (PPD) is a common disorder that affects 10-15% of postpartum women, and it can have negative effects on both the mother and newborn. Recent studies have suggested that low levels of vitamin D are associated with poor mood and depression. The aim of this prospective study was to evaluate a possible association between PPD and serum levels of 25-hydroxy vitamin D3 (25 (OH)D3), a reliable measurement of vitamin D, during mid-pregnancy.Study design: The source population consisted of all pregnant women between 24 and 28 gestational weeks from June 2012 to October 2012 at Bornova Health Research and Application Hospital, Sifa University. In order to better evaluate a possible effect between vitamin D levels and PPD, individuals with characteristics that put them at risk for developing PPD were excluded from the study. Serum 25 (OH)D3 levels were evaluated mid-pregnancy in the study group. Serum 25(OH)D3 concentrations