Assessing Regional Muscle Mass with Segmental Measurements of Bioelectrical Impedance in Obese Women during Weight Loss a, b
Assessing Regional Muscle Mass with Segmental Measurements of Bioelectrical Impedance in Obese Women during Weight Loss a, b
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通过分段测量生物电阻抗来评估肥胖女性减肥期间的区域肌肉质量 a、b
DOI：
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发表时间：
2000
影响因子：
5.2
通讯作者：
H. Lukaski
中科院分区：
文献类型：
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作者：
H. Lukaski
摘要：由于骨骼、脂肪和骨骼肌的电阻率差异很大，四极生物阻抗分析(BIA)提供了确定人体不同节段的生物导体体积的可能性。我们通过在受控减肥计划之前和期间测量BIA和对女性右大腿确定的节段进行人体测量来检验这一假设。8名女性，年龄22~32岁，体重指数为37.8±1.6(平均值±SE)kg/m2，在计划前采用双能X线骨密度仪和局部BIA测量(800μA，50 kHz)，并在减肥期间每月测量4个月。在大腿前部放置相距10 cm的斑点探测器电极，在右手和右脚放置源电极，进行BIA测量。在减重过程中，大腿部分的体积减少了29±3%(p<；0.0001)，电体积变化不大(8±0.2%；p<；0.05)。肌肉(181±49g；p<；0.05)和脂肪质量(702±95g；p<；0.001)也有所下降。电或生物导体体积与DXA测定的肌肉质量相关(r=0.91p<；0.0001)，而物理体积与脂肪质量相关(r=0.95p<；0.0001)。这些发现支持这样的假设，即BIA是评估人类局部肌肉质量的有效方法。
Abstract: Tetrapolar bioelectrical impedance analysis (BIA) offers the possibility of determining the bioconductor volume in discrete segments of the body, because the resistivities of bone, fat, and skeletal muscle differ considerably. We tested this hypothesis by measuring BIA and anthropometry of defined segments of the right thighs of women before and during a controlled weight‐loss program. Eight women, aged 22 to 32 years, with a body mass index of 37.8 ± 1.6 (mean ± SE) kg/m2 underwent determinations of body composition with dual‐energy X‐ray absorptiometry (DXA) and regional BIA measurements (800 μA at 50 kHz) before the program, and monthly thereafter for four months during weight loss. BIA measurements were made with spot‐detector electrodes positioned 10 cm apart on the anterior of the thigh, and source electrodes placed on the right hand and foot. The physical volume of the thigh segment decreased by 29 ± 3% (p < 0.0001), with a modest change in its electrical volume (8 ± 0.2%; p < 0.05) during weight loss. Muscle (181 ± 49 g; p < 0.05) and fat mass (702 ± 95 g; p < 0.001) also declined. The electrical or bioconductor volume correlated with DXA determinations of muscle mass (r= 0.91, p < 0.0001), whereas physical volume correlated with fat mass (r= 0.95, p < 0.0001). These findings support the hypothesis that BIA is a valid method to assess regional muscle mass in humans.