Pathogenesis of endometriosis
Pathogenesis of endometriosis
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DOI：
10.1016/j.bpobgyn.2004.01.005
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发表时间：
2004-04-01
影响因子：
5.5
通讯作者：
Dunselman, GAJ
中科院分区：
文献类型：
--
作者：
Nap, AW;Groothuis, PG;Dunselman, GAJ
许多妇女海港点腹膜子宫内膜异位症没有任何症状;这是被称为现象子宫内膜异位症。其中一些妇女继续发展症状性子宫内膜异位症。虽然我们知道可能参与子宫内膜异位症病因和发病机制的因素，但子宫内膜异位症发展为疾病子宫内膜异位症的确切机制及其相关体征和症状仍然不清楚。被广泛接受的理论是桑普森的移植理论。最近的研究结果表明，子宫内膜的某些特性以及局部环境的影响在子宫内膜异位症的发展中至关重要。早期子宫内膜异位症病变形成的详细描述，因为这似乎是一个关键的过程，在腹膜子宫内膜异位症的发展。
Many women harbour spots of peritoneal endometriosis without having any symptoms; this is referred to as the phenomenon endometriosis. Some of these women go on to develop symptomatic endometriosis. Although we know the factors potentially involved in the aetiology and pathogenesis of endometriosis, the exact mechanism by which the phenomenon endometriosis develops into the disease endometriosis, with its associated signs and symptoms, remain obscure. The widely accepted theory is Sampson's transplantation theory. Recent findings indicate that certain properties of the endometrium, and the influence of the local environment, are crucial in the development of endometriosis. Early endometriosis lesion formation is described in detail, as this seems to be a key process in the development of peritoneal endometriosis.