Synthesis of heterocyclic and carbocyclic fluoro-olefins by ring-closing metathesis.
Synthesis of heterocyclic and carbocyclic fluoro-olefins by ring-closing metathesis.
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DOI：
10.1021/ol035065w
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发表时间：
2003-08
期刊：
影响因子：
5.2
通讯作者：
Sofia S. Salim;R. Bellingham;V. Satcharoen;Richard C. D. Brown
中科院分区：
文献类型：
--
作者：
Sofia S. Salim;R. Bellingham;V. Satcharoen;Richard C. D. Brown
[反应：在钌亚烷基卡宾络合物11存在下，含氟乙烯的二烯的闭环复分解（RCM）有效地进行，得到六元和七元环状氟乙烯。RCM反应用于从简单的商业氟代烯烃制备胺和磺酰胺连接的环烯烃以及碳环体系。
[reaction: see text] Ring-closing metathesis (RCM) of vinyl fluoride-containing dienes in the presence of ruthenium alkylidene carbene complex 11 proceeded efficiently to give six- and seven-membered cyclic vinyl fluorides. The RCM reaction was used to prepare amine- and sulfamide-linked cyclo-olefins, as well as carbocyclic systems, from a simple commercial fluoro-olefin.