Reduction of diffusion-weighted MRI lesion volume after early moderate hypothermia in ischemic stroke
Reduction of diffusion-weighted MRI lesion volume after early moderate hypothermia in ischemic stroke
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DOI：
10.1161/01.str.0000166057.96174.88
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发表时间：
2005-06-01
期刊：
影响因子：
8.3
通讯作者：
Schwab, S
中科院分区：
文献类型：
--
作者：
Berger, C;Schramm, P;Schwab, S
Background - Large areas of restricted diffusion in the middle cerebral artery (MCA) territory are highly predictive of severe and potentially space-occupying MCA stroke. A reduction of diffusion-weighted MRI (DWI) lesions occurs in 20% to 40% of acute stroke patients with early reperfusion.Methods - We report of a patient with a severe stroke syndrome who was treated with early moderate hypothermia but not thrombolysis.Results - The initially large DWI deficit of the whole MCA territory contrasted to the relatively small final lesion restricted to the basal ganglia on MRI and computed tomography scan.Conclusion - This case describes an unexpected reduction of a DWI lesion after early moderate hypothermia and spontaneous recanalization 3 days after stroke onset. We discuss potential reasons for the unexpected DWI lesion reduction.
